{"id":"W4405044335","doi":"10.1182/blood-2024-197938","title":"Five-Year Analysis of the POLARIX Study: Prolonged Follow-up Confirms Positive Impact of Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) on Outcomes","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada); Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Prednisone; Rituximab; Medicine; Cyclophosphamide; Internal medicine; Doxorubicin; Oncology; Chemotherapy; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007638006,0.0007226352,0.001129157,0.0006567045,0.0003189648,0.001102374,0.0007909194,0.0007877958,0.003356234],"category_scores_gemma":[0.005288596,0.0003213744,0.002521764,0.001075209,0.000408479,0.0008141925,0.001171008,0.001755817,0.0002745717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005988035,"about_ca_system_score_gemma":0.0006873473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001459635,"about_ca_topic_score_gemma":0.001633838,"domain_scores_codex":[0.9977996,0.001064032,0.0001046431,0.0004930065,0.0002847822,0.0002539339],"domain_scores_gemma":[0.9934948,0.002182405,0.001939453,0.001067576,0.0003715764,0.0009442434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2608196,0.0007793647,0.6961052,0.0004932701,0.01227492,0.0004805352,0.0001625181,0.002777387,0.001806927,0.00037817,0.004297925,0.01962413],"study_design_scores_gemma":[0.01937028,0.01786195,0.945,0.00007383018,0.008572444,0.0004483529,0.0001243414,0.003881668,0.0008019421,0.0004162526,0.003395015,0.00005386378],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919342,0.002126565,0.0004511574,0.000147512,0.00003597552,0.0001008899,0.004303599,0.00001807668,0.0008819718],"genre_scores_gemma":[0.9905827,0.0003756951,0.000191542,0.000173735,0.00006213727,0.000100182,0.007956345,0.00001045078,0.0005471777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007638006,"threshold_uncertainty_score":0.04039413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009204980291732019,"score_gpt":0.2851370144965988,"score_spread":0.2759320342048668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}