{"id":"W4405044434","doi":"10.1182/blood-2024-193946","title":"Sinusoidal Obstruction Syndrome in Children with CD22+ B-Cell Precursors Acute Lymphoblastic Leukemia (BCP-ALL) Treated with Inotuzumab Ozogamicin in Trial ITCC-059: Risk Factors and Outcomes","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"CD22; Medicine; Lymphoblastic Leukemia; Internal medicine; Pediatrics; Leukemia; CD20; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002563868,0.0006502466,0.0009987409,0.001025583,0.00007576686,0.00013031,0.0002065467,0.0003658404,0.0000357223],"category_scores_gemma":[0.0001450464,0.0004243162,0.0001097455,0.001209136,0.0002704508,0.000318752,0.0001035099,0.0008232812,0.00002762647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002049503,"about_ca_system_score_gemma":0.001450911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004135444,"about_ca_topic_score_gemma":0.0005854667,"domain_scores_codex":[0.9964799,0.0001776578,0.0006366551,0.001026252,0.0008288567,0.0008506595],"domain_scores_gemma":[0.998523,0.0004570831,0.0001492697,0.0004800587,0.00006254223,0.0003280731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01157196,0.0008731341,0.9814579,0.0001777447,0.001538969,0.001961415,0.0009243904,0.0001845608,0.000578511,0.00001223035,0.00002999166,0.0006892201],"study_design_scores_gemma":[0.1714551,0.004330433,0.8124637,0.000632778,0.001790394,0.003449953,0.0002612997,0.001845718,0.003178514,0.00002240249,0.00001160987,0.0005580721],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969127,0.0002202724,0.00003104097,0.0000590784,0.00008893623,0.002169051,0.0001205571,0.0002232325,0.0001751107],"genre_scores_gemma":[0.9985902,0.0001238336,0.0003341537,0.00002422699,0.00007637923,0.0001091802,0.0001539459,0.0001360281,0.0004520597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1689942,"threshold_uncertainty_score":0.9998209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007429589898990763,"score_gpt":0.2393044221542287,"score_spread":0.231874832255238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}