{"id":"W4405045169","doi":"10.1182/blood-2024-201058","title":"10 Year Follow-up of CALGB 10603/Ratify: Midostaurin Versus Placebo Plus Intensive Chemotherapy in Newly Diagnosed <i>FLT3</i> Mutant Acute Myeloid Leukemia Patients Aged 18-60 Years","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Midostaurin; Medicine; Myeloid leukemia; Chemotherapy regimen; Internal medicine; Chemotherapy; Oncology; Cytarabine; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002494129,0.0005636275,0.001711605,0.0003937484,0.0005493268,0.0008520331,0.0004627507,0.00124209,0.002211939],"category_scores_gemma":[0.00151337,0.0002795894,0.00181494,0.0004580246,0.0004762341,0.0007052221,0.0005151024,0.002352467,0.0003956974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001110271,"about_ca_system_score_gemma":0.0008076013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00235559,"about_ca_topic_score_gemma":0.003397847,"domain_scores_codex":[0.9994154,0.0002055191,0.00005031835,0.0001202962,0.00006934349,0.0001392354],"domain_scores_gemma":[0.9985416,0.0002392616,0.0004915044,0.00009858187,0.00009048866,0.0005386719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8166889,0.01796201,0.07686496,0.0002720544,0.002785417,0.0003577646,0.0002461827,0.001438034,0.005345441,0.0001936738,0.00367339,0.07417216],"study_design_scores_gemma":[0.166328,0.5007624,0.3203569,0.0001403012,0.003842438,0.0004771161,0.0002464303,0.002064549,0.001825219,0.0003543148,0.00353617,0.00006624147],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955154,0.001912293,0.0001365925,0.0002640366,0.00008865127,0.0002005813,0.0008770259,0.00001758884,0.0009878067],"genre_scores_gemma":[0.9964055,0.0005710759,0.000131299,0.0005327471,0.0001081712,0.0001566978,0.001437525,0.000003568281,0.0006534464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002494129,"threshold_uncertainty_score":0.01319039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01727424317486516,"score_gpt":0.2782159156701849,"score_spread":0.2609416724953198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}