{"id":"W4405046742","doi":"10.1182/blood-2024-210038","title":"Don't Fly and Freeze: Impact of Ex-Vivo-Time, Cell Concentration and Cryopreservation on the Composition of Allogeneic Stem Cell Grafts","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Cryopreservation; Leukapheresis; Andrology; Stem cell; Viability assay; Apheresis; Biology; Ex vivo; Immunology; Transplantation; CD34; Medicine; Cell; In vivo; Internal medicine; Biotechnology; Cell biology; Biochemistry; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005793143,0.0001379216,0.0001501711,0.000197893,0.0001888187,0.0005272283,0.00017325,0.0001254693,0.001125194],"category_scores_gemma":[0.0004237337,0.00006266542,0.0001689824,0.0001778643,0.0001779739,0.0002199729,0.0001430006,0.0001942739,0.0001645215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002786753,"about_ca_system_score_gemma":0.0001596883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008932277,"about_ca_topic_score_gemma":0.001432876,"domain_scores_codex":[0.9997638,0.00006752434,0.00002047417,0.00004686798,0.00006637839,0.0000349946],"domain_scores_gemma":[0.999586,0.0001478363,0.0001082243,0.00003468175,0.00006780055,0.00005544899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01448949,0.001313665,0.283748,0.0002333299,0.0002019308,0.0005956459,0.0005595906,0.002759313,0.6113485,0.0002484474,0.0005700828,0.08393206],"study_design_scores_gemma":[0.00007940141,0.008538399,0.4304925,0.00004243053,0.0002846146,0.001284309,0.0005881962,0.003780007,0.5515634,0.0001598314,0.003159491,0.0000272696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984851,0.0006842506,0.0002947191,0.00001615389,0.000008677912,0.00001258738,0.00008916837,0.000004177816,0.0004051841],"genre_scores_gemma":[0.9985538,0.0002927027,0.0004264387,0.00003642798,0.000007273661,0.00001331633,0.0002532807,0.000005453043,0.0004112848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001125194,"threshold_uncertainty_score":0.003764153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01320120185642252,"score_gpt":0.24550437281516,"score_spread":0.2323031709587375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}