{"id":"W4405049412","doi":"10.1182/blood-2024-202728","title":"Point-of-Care Bispectral Electroencephalogram (BSEEG) As a New Tool in Detecting Immune Effector Cell Associated Neurotoxicity (ICANS) in Patients Treated with Chimeric Antigen Receptor T-Cell (CAR-T)","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Neuroscience and Neural Engineering","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Neurotoxicity; Immune system; Antigen; Cell; Chimeric antigen receptor; Medicine; Effector; T cell; Immunology; Internal medicine; Chemistry; Toxicity; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001298792,0.0003557707,0.0004174952,0.0004502696,0.00007520067,0.0001050912,0.000399718,0.00009708557,0.00001803799],"category_scores_gemma":[0.0004902075,0.0003137896,0.0001220395,0.003015641,0.00006870083,0.0003716782,0.00007002422,0.0005941238,0.000019281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001030627,"about_ca_system_score_gemma":0.0001597654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003158304,"about_ca_topic_score_gemma":0.00004280666,"domain_scores_codex":[0.9973071,0.0002001439,0.0004581275,0.0008267169,0.0004243409,0.0007836363],"domain_scores_gemma":[0.9992067,0.0002422479,0.0001288887,0.0002731397,0.00002460923,0.0001244713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009114594,0.0004904717,0.04558571,0.00008234598,0.000003774024,0.0001341432,0.0002841313,0.00009745024,0.9526861,0.000002227792,0.000003796952,0.0005387369],"study_design_scores_gemma":[0.002165177,0.002503656,0.04767194,0.0001952726,0.00002177782,0.000009334714,0.00001692908,0.0007494527,0.94634,0.00000333143,0.00001625415,0.0003068586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981752,0.0001773361,0.000007507635,0.00001791548,0.000187674,0.001016493,0.00001675992,0.0002457197,0.000155382],"genre_scores_gemma":[0.999594,0.00007179141,0.00005677913,0.00006824765,0.00002502649,0.00004385294,0.000006372512,0.00006336812,0.0000705503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006346045,"threshold_uncertainty_score":0.9999314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006298919154708133,"score_gpt":0.2092743721571232,"score_spread":0.2029754530024151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}