{"id":"W4405049724","doi":"10.1016/s2468-1253(24)00311-x","title":"International consensus statement on microbiome testing in clinical practice","year":2024,"lang":"en","type":"review","venue":"˜The œLancet. Gastroenterology & hepatology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Ministero dell'Istruzione e del Merito; H2020 European Research Council; Agencia Estatal de Investigación; Medical Research Council; Horizon 2020 Framework Programme; National Institutes of Health; Grifols; National Heart, Lung, and Blood Institute; Fondazione Roma; Ipsen; Aboca S.p.A. Società Agricola; Celltrion; Eisai; Astellas Pharma; Eli Lilly and Company; Associazione Italiana per la Ricerca sul Cancro; Gastroenterological Society of Australia; Chinese University of Hong Kong; Janssen Pharmaceuticals; Ministero dell’Istruzione, dell’Università e della Ricerca; Novo Nordisk; Dr. Falk Pharma; National Institute for Health and Care Research; Imperial College Healthcare NHS Trust; Imperial College London; Danone; Tillotts Pharma; Fonds De La Recherche Scientifique - FNRS; European Research Council; Ministerio de Ciencia, Innovación y Universidades; Celgene; National Cancer Institute; HORIZON EUROPE Framework Programme; Servier; Gilead Sciences; Amgen; National Health and Medical Research Council; Walloon excellence in life sciences and biotechnology; Seres Therapeutics; Sanofi; Ministero della Salute; Pfizer","keywords":"Microbiome; Multidisciplinary approach; Human microbiome; Medicine; Clinical Practice; Health care; Risk analysis (engineering); Engineering ethics; Intensive care medicine; Bioinformatics; Engineering; Nursing; Political science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001934997,0.0006030952,0.001941193,0.0002636492,0.00008630737,0.0000424262,0.0009600468,0.0008111801,0.00002392734],"category_scores_gemma":[0.0003758335,0.0004478138,0.0004266048,0.0001766122,0.0004721923,0.000003162978,0.0006238777,0.001662686,0.0002868888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001751091,"about_ca_system_score_gemma":0.0005167875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005391874,"about_ca_topic_score_gemma":0.0004902006,"domain_scores_codex":[0.9939727,0.00178423,0.00186886,0.001219831,0.0001274114,0.001026924],"domain_scores_gemma":[0.9976115,0.000417581,0.0008426882,0.0008707986,0.0001386491,0.0001188298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003218861,0.00175986,0.02307231,0.007169832,0.004422751,0.002330979,0.0001075135,0.00001072261,0.001430692,0.0003193765,0.6084638,0.3476934],"study_design_scores_gemma":[0.0009778438,0.001160683,0.0002030197,0.0008005851,0.0004247921,0.002809398,0.00001850249,0.00001607698,0.000001744305,0.00001526547,0.9933577,0.0002143755],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009733091,0.9702774,0.0000748418,0.009832631,0.006432832,0.00147468,0.0005493023,0.00006990632,0.00155527],"genre_scores_gemma":[0.002222368,0.98452,0.001655959,0.008562977,0.00181508,0.0001597801,0.0007122742,0.00009550882,0.0002561017],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.384894,"threshold_uncertainty_score":0.9997973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09247315966298914,"score_gpt":0.4239894490229076,"score_spread":0.3315162893599184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}