{"id":"W4405050250","doi":"10.1182/blood-2024-211936","title":"Can Optical Genome Mapping Replace Bone Marrow Biopsies in Acute Myeloid Leukemia?","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Bone marrow; Myeloid leukemia; Leukemia; Medicine; Cancer research; Pathology; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001932375,0.0004268914,0.000628867,0.000792921,0.0002914662,0.000525199,0.0005565096,0.0005402046,0.0009883119],"category_scores_gemma":[0.004124282,0.0002503743,0.0002024508,0.0006917795,0.0005305292,0.0006688244,0.0004921212,0.0004421567,0.0006227713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002218056,"about_ca_system_score_gemma":0.0002931595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009607643,"about_ca_topic_score_gemma":0.002277772,"domain_scores_codex":[0.9994499,0.0001946234,0.00006300746,0.00008970038,0.0001407218,0.00006206736],"domain_scores_gemma":[0.9986771,0.0004549729,0.0003656448,0.0001442758,0.0002090263,0.0001490143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000826253,0.0000586603,0.9022791,0.0001478226,0.00003789435,0.003123919,0.0002116986,0.0001890153,0.01687032,0.0001150722,0.0008194111,0.07532088],"study_design_scores_gemma":[0.00007115612,0.001162724,0.9442149,0.0001776847,0.0001219437,0.03065705,0.0009702805,0.002796066,0.010905,0.0008331271,0.008065924,0.00002423201],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881016,0.005387838,0.004325378,0.0006189847,0.00009364814,0.00007883512,0.0001480142,0.00006732626,0.001178371],"genre_scores_gemma":[0.987205,0.003159608,0.008462302,0.0004967703,0.0001168798,0.00004347408,0.0002354669,0.00002275266,0.0002577834],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001932375,"threshold_uncertainty_score":0.01021945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01768950015925802,"score_gpt":0.272891301789172,"score_spread":0.255201801629914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}