{"id":"W4405051123","doi":"10.1182/blood-2024-201875","title":"Efficacy and Safety of Revumenib in the Treatment of Acute Myeloid Leukemia with KMT2A Rearrangements or NPM1 Mutations: A Systematic Review","year":2024,"lang":"en","type":"review","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"NPM1; Myeloid leukemia; Medicine; Oncology; Internal medicine; Leukemia; Myeloid; Bone marrow; Cancer research; Biology; Genetics; Karyotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005735022,0.001320433,0.00898362,0.00517734,0.000423873,0.001761957,0.001631755,0.001438544,0.003743925],"category_scores_gemma":[0.01784781,0.0006908657,0.01060969,0.006055541,0.0005872569,0.001314668,0.0009256579,0.0008296786,0.000285923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002322881,"about_ca_system_score_gemma":0.005891737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005635468,"about_ca_topic_score_gemma":0.01639675,"domain_scores_codex":[0.995931,0.001465514,0.001509392,0.0003598119,0.0006044103,0.0001299843],"domain_scores_gemma":[0.989488,0.006982949,0.002095688,0.0001751227,0.001125614,0.0001326138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0004089537,0.00001144674,0.0006601192,0.9471403,0.03106634,0.00006052039,0.00006885736,0.0001618877,0.0002101932,0.0001340489,0.0009737026,0.01910358],"study_design_scores_gemma":[0.000881458,0.0004906055,0.00565758,0.5622091,0.4117077,0.0003752192,0.0001720249,0.0002254739,0.0003484572,0.000465154,0.01741428,0.00005304664],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001642031,0.9967192,0.0001657262,0.0001811415,0.00007407474,0.0002646129,0.0006429197,0.000009534329,0.0003007512],"genre_scores_gemma":[0.03371304,0.963688,0.0006573062,0.0006605556,0.0001030794,0.0005625729,0.0004597153,0.000008929172,0.0001468089],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00898362,"threshold_uncertainty_score":0.03033006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04547199090986818,"score_gpt":0.3658874416028316,"score_spread":0.3204154506929634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}