{"id":"W4405051335","doi":"10.1182/blood-2024-203473","title":"Canadian Real-World Data for Acute Myeloid Leukemia Chemotherapy-Ineligible Patients on Venetoclax: An Interim Analysis from the Prospective Liven Study","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Cancer Centre; BC Cancer Agency; University of British Columbia; Baker Hughes (Canada); Vancouver General Hospital; University of Calgary; Memorial University of Newfoundland; Thunder Bay Regional Research Institute; Université de Sherbrooke; London Health Sciences Centre; CancerCare Manitoba","funders":"","keywords":"Venetoclax; Medicine; Internal medicine; Interim analysis; Cytarabine; Chemotherapy regimen; Regimen; Myeloid leukemia; Induction chemotherapy; Oncology; Pediatrics; Leukemia; Clinical trial; Chemotherapy; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00811862,0.0006044098,0.001111141,0.001177679,0.001637689,0.001338992,0.001665048,0.0005279537,0.002954745],"category_scores_gemma":[0.01155409,0.0003644738,0.002486713,0.003290256,0.0005788148,0.0004087799,0.001019744,0.00122246,0.0003993256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01117136,"about_ca_system_score_gemma":0.02011879,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.7897991,"about_ca_topic_score_gemma":0.8036164,"domain_scores_codex":[0.993696,0.001307361,0.0004010182,0.0006896478,0.002696795,0.001209226],"domain_scores_gemma":[0.9884164,0.001609195,0.002421427,0.002279477,0.004249691,0.001023859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01910057,0.0004235353,0.9418299,0.0003365455,0.002314897,0.0001675917,0.0003878956,0.002724514,0.000507564,0.0008777223,0.01548511,0.01584422],"study_design_scores_gemma":[0.001641539,0.001301903,0.9781564,0.00009796902,0.001178133,0.0001223274,0.0002738523,0.001634862,0.0003333856,0.0001323709,0.0150522,0.00007492478],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7781166,0.001518926,0.002014288,0.0005445087,0.00006843136,0.001871605,0.2084189,0.0001004632,0.007346204],"genre_scores_gemma":[0.8231274,0.0004661439,0.002377434,0.0005226503,0.00003693832,0.001371427,0.1698769,0.00003621347,0.002184977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2102009,"threshold_uncertainty_score":0.4228776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03642554603829051,"score_gpt":0.3586358739182737,"score_spread":0.3222103278799832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}