{"id":"W4405051936","doi":"10.1182/blood-2024-201980","title":"Targeting PRMT5-Mediated DNA Repair Pathway in Extra-Nodal NK/T-Cell Lymphoma (ENKTL)","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"T-cell lymphoma; Lymphoma; Cancer research; Biology; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002207755,0.0001782699,0.0001318655,0.00008789205,0.00004101844,0.00003293416,0.0001123483,0.00027188,0.00003274142],"category_scores_gemma":[0.000064397,0.000185411,0.0001209903,0.0002487689,0.00003618214,0.000006296642,0.00006950548,0.00009197182,0.00005188636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000413662,"about_ca_system_score_gemma":0.000219587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003021541,"about_ca_topic_score_gemma":0.00004445049,"domain_scores_codex":[0.9986978,0.00006100442,0.0002926226,0.0004988526,0.0001454231,0.0003042517],"domain_scores_gemma":[0.9995517,0.00001918082,0.00005047841,0.0002719189,0.0000362524,0.00007050886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002978937,0.000228887,0.0007503129,0.00008949192,0.0000555287,0.00004769987,0.0000992842,0.0001554753,0.9948819,0.00002581948,0.001648671,0.001987125],"study_design_scores_gemma":[0.002290439,0.0001932368,0.001420969,0.00009129183,0.00004026583,0.00004168641,0.00005450311,0.002387155,0.9161428,0.00005138634,0.07692438,0.0003619087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853159,0.01225276,0.000116286,0.00007345938,0.0003730491,0.000218475,0.00002999589,0.000125685,0.001494377],"genre_scores_gemma":[0.9971444,0.0002955286,0.0004543887,0.00004850785,0.0005122953,0.00003619645,0.0004036363,0.00004986916,0.001055194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07873914,"threshold_uncertainty_score":0.756084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004760233435654468,"score_gpt":0.2046829522103933,"score_spread":0.1999227187747388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}