{"id":"W4405056433","doi":"10.1172/jci.insight.185307","title":"Granzyme A as biomarker for diagnosis in tuberculous pleural effusion","year":2024,"lang":"en","type":"article","venue":"JCI Insight","topic":"Pleural and Pulmonary Diseases","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Shenzhen University; Natural Science Foundation of Guangdong Province","keywords":"Biomarker; Medicine; Pleural effusion; Granzyme B; Internal medicine; Mesothelioma; Pathology; Immunology; Biology; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006568857,0.0001466442,0.0002144913,0.0001863618,0.0000445142,0.00003141502,0.00005732893,0.0000801572,0.0005582061],"category_scores_gemma":[0.00009261611,0.0001021886,0.0001715189,0.0003319583,0.00003239695,0.0001115299,0.00003303252,0.00009955189,0.0002112238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005517399,"about_ca_system_score_gemma":0.00006945313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001308192,"about_ca_topic_score_gemma":0.00004799713,"domain_scores_codex":[0.9990975,0.0000248459,0.0002002539,0.0002823057,0.0001635956,0.0002315409],"domain_scores_gemma":[0.9994966,0.0001750595,0.00001381705,0.0001442108,0.0000284851,0.0001418585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004541451,0.00297158,0.221814,0.00405857,0.0004211747,0.01294205,0.003038473,0.000007422154,0.04292855,0.004426455,0.412383,0.2904673],"study_design_scores_gemma":[0.001714661,0.0006434011,0.1966362,0.0009349372,0.0002017948,0.0002685595,0.00006948916,0.00433095,0.003501927,0.002426509,0.7889414,0.0003302276],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772903,0.008915163,0.000005138996,0.006481599,0.0004294291,0.0005800388,0.00005800132,0.0001390014,0.00610134],"genre_scores_gemma":[0.9945796,0.0003519859,0.00005386895,0.001069361,0.0002241294,0.0002801848,0.0001561254,0.00002590683,0.003258845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3765584,"threshold_uncertainty_score":0.6111965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03173021072290667,"score_gpt":0.3119032190315494,"score_spread":0.2801730083086428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}