{"id":"W4405056433","doi":"10.1172/jci.insight.185307","title":"Granzyme A as biomarker for diagnosis in tuberculous pleural effusion","year":2024,"lang":"en","type":"article","venue":"JCI Insight","topic":"Pleural and Pulmonary Diseases","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Shenzhen University; Natural Science Foundation of Guangdong Province","keywords":"Biomarker; Medicine; Pleural effusion; Granzyme B; Internal medicine; Mesothelioma; Pathology; Immunology; Biology; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004800192,0.001417531,0.001154283,0.001346012,0.0003744915,0.001844765,0.000951169,0.001166837,0.001030139],"category_scores_gemma":[0.009551367,0.0004088275,0.001328817,0.0008141797,0.0005371824,0.000928544,0.0008798732,0.001563561,0.0004241248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005866267,"about_ca_system_score_gemma":0.0006480365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000733179,"about_ca_topic_score_gemma":0.000707258,"domain_scores_codex":[0.998492,0.0007469858,0.0001330389,0.0003184071,0.0001773046,0.0001321813],"domain_scores_gemma":[0.9949366,0.002736737,0.001279712,0.0002734086,0.0004344332,0.0003390496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003982509,0.0002441141,0.9271044,0.0003054754,0.0007198036,0.0004330892,0.00008264824,0.007904493,0.006367727,0.0002755874,0.001108191,0.05147196],"study_design_scores_gemma":[0.00116837,0.006604915,0.6347765,0.0008820805,0.003050419,0.008493858,0.0004662583,0.2935903,0.03083927,0.008678819,0.01122395,0.0002252034],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9462188,0.03028566,0.01934863,0.001286911,0.0002994402,0.0002063041,0.001064333,0.0002471099,0.00104279],"genre_scores_gemma":[0.9928442,0.001688392,0.004555528,0.000153557,0.0001008691,0.00006153031,0.0003863448,0.000009099885,0.0002005324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004800192,"threshold_uncertainty_score":0.0253861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03173021072290667,"score_gpt":0.3119032190315494,"score_spread":0.2801730083086428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}