{"id":"W4405060488","doi":"10.1002/ange.202419996","title":"Self‐Assembly and Biological Properties of Highly Fluorinated Oligonucleotide Amphiphiles","year":2024,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"European Regional Development Fund; Fonds de recherche du Québec – Nature et technologies; Regione Lombardia; Natural Sciences and Engineering Research Council of Canada; European Commission; Ministero della Salute; Canada Foundation for Innovation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Nucleic acid; Oligonucleotide; Amphiphile; Nanocarriers; Molecular beacon; DNA; Chemistry; Small molecule; Combinatorial chemistry; Nanotechnology; Biophysics; Computational biology; Biochemistry; Biology; Nanoparticle; Materials science; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002062242,0.0002118789,0.00005634121,0.0001749669,0.0001017553,0.0001794436,0.0000765761,0.0002371184,0.0003221996],"category_scores_gemma":[0.0003478221,0.00009464836,0.0001038752,0.00008182291,0.0001690546,0.0001890909,0.0001236036,0.0001740564,0.0001190776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001597298,"about_ca_system_score_gemma":0.0001071268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004616963,"about_ca_topic_score_gemma":0.0003833344,"domain_scores_codex":[0.999915,0.00001743983,0.000006650056,0.00001946374,0.00002393033,0.00001742955],"domain_scores_gemma":[0.9998031,0.00004448627,0.00006547913,0.000008243278,0.00004192651,0.00003683053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002218803,0.00000736291,0.0001231731,0.00001091322,0.00000201101,0.00001294006,0.00001441563,0.00009089783,0.9990395,0.00005235283,0.00001014835,0.0006140787],"study_design_scores_gemma":[0.000004143098,0.0001327249,0.001893681,0.000002194222,0.000004145897,0.00004391986,0.000008854277,0.001643429,0.9957055,0.0000180625,0.0005386155,0.000004756015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970378,0.0005155238,0.001875807,0.00002000902,0.000006870406,0.000009919999,0.00006093129,0.00001737223,0.0004557802],"genre_scores_gemma":[0.9978805,0.0001611128,0.001263832,0.00001212304,0.000003046561,0.000009725316,0.00007256272,0.000005415117,0.0005916859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004616963,"threshold_uncertainty_score":0.001158893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01727415123210322,"score_gpt":0.2485644218344724,"score_spread":0.2312902706023692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}