{"id":"W4405077348","doi":"10.3390/vaccines12121372","title":"The Impact of HIV on B Cell Compartment and Its Implications for COVID-19 Vaccinations in People with HIV","year":2024,"lang":"en","type":"review","venue":"Vaccines","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; St. Paul's Hospital; Centre Hospitalier Universitaire Sainte-Justine; Centre for Advancing Health Outcomes; McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé","keywords":"Germinal center; Memory B cell; Immunology; Immune system; B cell; B-1 cell; Antibody; Biology; Virology; Vaccination; Polyclonal B cell response; Naive B cell; Antigen; Medicine; T cell; B-cell receptor; Antigen-presenting cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003237858,0.0003188454,0.0009778794,0.0004561835,0.0001348202,0.00004875923,0.0002228976,0.0001149808,0.000007228392],"category_scores_gemma":[0.0002366582,0.0001575986,0.0002969948,0.0008197174,0.00001298778,0.00003292052,0.00007351607,0.0002736797,0.00003172442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003852679,"about_ca_system_score_gemma":0.001650842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007638856,"about_ca_topic_score_gemma":0.0002776381,"domain_scores_codex":[0.9985825,0.00006902577,0.0004749048,0.0004036193,0.000166181,0.0003037718],"domain_scores_gemma":[0.9978615,0.001241497,0.0001679357,0.0004825119,0.0001616897,0.00008485688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00261632,0.004536089,0.06850434,0.2750022,0.004245832,0.0000675789,0.002514004,0.00005338166,0.0002299116,0.0161941,0.3082173,0.3178189],"study_design_scores_gemma":[0.001385428,0.0005456077,0.003151475,0.002022779,0.0007612748,0.00005130039,0.00004775772,0.000166976,0.00003043506,0.0001727525,0.9914723,0.0001919158],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002517151,0.9905445,0.00003954242,0.002137415,0.00003587102,0.003761234,0.0004376751,0.00004107131,0.0004855174],"genre_scores_gemma":[0.006202278,0.9892248,0.00003714477,0.0009611911,0.000173058,0.002554585,0.0001729315,0.00009476072,0.0005792349],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.683255,"threshold_uncertainty_score":0.6426683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1001205359287169,"score_gpt":0.455432756646416,"score_spread":0.3553122207176991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}