{"id":"W4405077348","doi":"10.3390/vaccines12121372","title":"The Impact of HIV on B Cell Compartment and Its Implications for COVID-19 Vaccinations in People with HIV","year":2024,"lang":"en","type":"review","venue":"Vaccines","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; St. Paul's Hospital; Centre Hospitalier Universitaire Sainte-Justine; Centre for Advancing Health Outcomes; McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé","keywords":"Germinal center; Memory B cell; Immunology; Immune system; B cell; B-1 cell; Antibody; Biology; Virology; Vaccination; Polyclonal B cell response; Naive B cell; Antigen; Medicine; T cell; B-cell receptor; Antigen-presenting cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005005178,0.0002521999,0.0004172953,0.0008538569,0.0002000064,0.0007275493,0.0002088116,0.0008346658,0.001620755],"category_scores_gemma":[0.001043451,0.0001063549,0.0003317992,0.0005378049,0.0003107758,0.000787201,0.0003479512,0.001160079,0.0006030426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004877027,"about_ca_system_score_gemma":0.0005832051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00133778,"about_ca_topic_score_gemma":0.001486644,"domain_scores_codex":[0.9997523,0.00007947569,0.00004980267,0.00003442681,0.00005398424,0.00002989766],"domain_scores_gemma":[0.9995912,0.0002233025,0.00005151212,0.000006906708,0.00009338838,0.00003373962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002985743,0.00006373051,0.004538196,0.01044667,0.000108484,0.001281549,0.0004742699,0.0002873536,0.003143111,0.005699475,0.05545573,0.9182029],"study_design_scores_gemma":[0.00001858249,0.0004493631,0.0140972,0.007525769,0.0002525444,0.01205145,0.0003879229,0.0001783778,0.0013301,0.002524501,0.9611465,0.00003771945],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001214336,0.9937804,0.0001480505,0.002499577,0.0005215607,0.000005750437,0.00003700352,0.000009968019,0.001783353],"genre_scores_gemma":[0.01004853,0.9837335,0.0003388539,0.001992109,0.00200266,0.0000162304,0.00008234463,0.000006804312,0.001779089],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001620755,"threshold_uncertainty_score":0.005421996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1001205359287169,"score_gpt":0.455432756646416,"score_spread":0.3553122207176991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}