{"id":"W4405088732","doi":"10.1002/npr2.12509","title":"Efficacy and safety of lemborexant in subjects with insomnia disorder receiving medications for depression or anxiety symptoms","year":2024,"lang":"en","type":"article","venue":"Neuropsychopharmacology Reports","topic":"Sleep and related disorders","field":"Psychology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Ottawa Mental Health Centre","funders":"Eisai Canada","keywords":"Anxiety; Placebo; Insomnia; Population; Depression (economics); Medicine; Randomized controlled trial; Psychiatry; Internal medicine; Sleep disorder; Sleep onset; Psychology; Physical therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00115846,0.0003729103,0.0008966783,0.0002343047,0.0002965367,0.0003070669,0.0002721842,0.0006053708,0.003100721],"category_scores_gemma":[0.001100093,0.0002039712,0.0007898514,0.0001969,0.0002820645,0.0002752831,0.0001937606,0.0006500441,0.0004235271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003103553,"about_ca_system_score_gemma":0.0004160925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005523039,"about_ca_topic_score_gemma":0.001974033,"domain_scores_codex":[0.9996314,0.0002035059,0.00004221868,0.00004562873,0.00003822206,0.0000390249],"domain_scores_gemma":[0.9994048,0.0001530289,0.0002497095,0.0000350835,0.00004548824,0.0001119362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7426562,0.01256841,0.02963373,0.00197857,0.00171687,0.0002204242,0.0002407794,0.0003617117,0.04875024,0.00006227948,0.00115665,0.1606541],"study_design_scores_gemma":[0.1857799,0.5666716,0.2371722,0.0001918688,0.00162802,0.0003511947,0.0001684064,0.0006512742,0.004734475,0.00009824877,0.002520712,0.00003232475],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930578,0.005204915,0.000166811,0.000157747,0.00004364866,0.0003155248,0.0002604963,0.00003568406,0.000757263],"genre_scores_gemma":[0.9962617,0.001635977,0.0003685436,0.0003840071,0.0001322735,0.0002749843,0.000320002,0.000004398538,0.000617997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003100721,"threshold_uncertainty_score":0.01037294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008847853756365388,"score_gpt":0.3170689237414162,"score_spread":0.3082210699850508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}