{"id":"W4405096023","doi":"10.1182/blood-2024-203181","title":"Golseek-2: A Phase 2 Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Golcadomide in Combination with Rituximab in Participants with Newly Diagnosed Advanced Stage Follicular Lymphoma","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Rituximab; Follicular lymphoma; Medicine; Open label; Oncology; Internal medicine; Phases of clinical research; Lymphoma; Randomized controlled trial; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002745936,0.001864459,0.002920614,0.0004179818,0.0005564701,0.001240904,0.0009932918,0.00215927,0.007707789],"category_scores_gemma":[0.001586407,0.0007992267,0.001884864,0.0003337958,0.001406457,0.001623594,0.0006524384,0.003572432,0.001559894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001330625,"about_ca_system_score_gemma":0.001914998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007182299,"about_ca_topic_score_gemma":0.001840547,"domain_scores_codex":[0.9991568,0.0003903341,0.00004061735,0.0001843419,0.00007378316,0.0001541253],"domain_scores_gemma":[0.9985545,0.0002408087,0.0003208584,0.0001051345,0.0001231473,0.0006555225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9338409,0.0343454,0.002131322,0.0006456123,0.001342196,0.00006929637,0.00009842989,0.0002870704,0.005710142,0.0001166501,0.001394701,0.02001818],"study_design_scores_gemma":[0.8359127,0.159022,0.002678721,0.00002564787,0.0004435827,0.00005685753,0.00003555214,0.0002587276,0.000366068,0.000157429,0.001026687,0.00001602864],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829723,0.003502019,0.0007436926,0.0009252182,0.0003903912,0.0079156,0.001822525,0.0001485578,0.001579583],"genre_scores_gemma":[0.9750122,0.002029393,0.0025195,0.002598505,0.0004954216,0.01186251,0.001952069,0.00004283604,0.003487637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007707789,"threshold_uncertainty_score":0.02578509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02673293755314466,"score_gpt":0.3393171476816203,"score_spread":0.3125842101284756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}