{"id":"W4405096106","doi":"10.1182/blood-2024-205767","title":"Odyssey: A Phase 2 Open-Label Study of Momelotinib in Combination with Luspatercept in Patients with Transfusion-Dependent Myelofibrosis","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Myelofibrosis; Medicine; Open label; Phases of clinical research; Ruxolitinib; Surgery; Internal medicine; Clinical trial; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001008422,0.001115978,0.001729595,0.0003148942,0.0003495877,0.001228602,0.00075219,0.001116605,0.006505354],"category_scores_gemma":[0.0007496372,0.0004551063,0.001166322,0.0002343283,0.0006726088,0.001165023,0.0003768904,0.003240417,0.00115894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007322051,"about_ca_system_score_gemma":0.001335597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009315534,"about_ca_topic_score_gemma":0.002829365,"domain_scores_codex":[0.9997777,0.00007684605,0.00001021318,0.00004643366,0.00002721719,0.00006153168],"domain_scores_gemma":[0.9996824,0.00004048715,0.00005601338,0.0000226455,0.00003026217,0.0001681588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.569795,0.1100705,0.004573449,0.003475851,0.002707975,0.0004719994,0.0006509462,0.003662937,0.04424023,0.00123042,0.01886318,0.2402574],"study_design_scores_gemma":[0.7394482,0.2358543,0.008831882,0.000135137,0.0005817385,0.000467047,0.0001313628,0.00278951,0.002286301,0.0006093176,0.008803966,0.00006123765],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776277,0.00744655,0.001229056,0.001435795,0.0004606376,0.003508161,0.002244084,0.0003302062,0.005717687],"genre_scores_gemma":[0.9765586,0.004901655,0.002620742,0.002861801,0.000210698,0.003362742,0.002764048,0.00004823966,0.006671498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006505354,"threshold_uncertainty_score":0.02176255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02033822022441533,"score_gpt":0.297506286240049,"score_spread":0.2771680660156337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}