{"id":"W4405103398","doi":"10.1111/tpj.17199","title":"An independent biosynthetic route to frame a xanthanolide‐type sesquiterpene lactone in Asteraceae","year":2024,"lang":"en","type":"article","venue":"The Plant Journal","topic":"Sesquiterpenes and Asteraceae Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Sesquiterpene; Sesquiterpene lactone; Lactone; Germacrene; Stereochemistry; Asteraceae; Biosynthesis; Ring (chemistry); Chemistry; Biology; Biochemistry; Botany; Organic chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004457182,0.000200907,0.000183211,0.0001341574,0.0001315886,0.0003019951,0.0003763762,0.00008346737,0.00009143255],"category_scores_gemma":[0.00003271508,0.000128565,0.0000788392,0.0001790308,0.00003389611,0.00001682183,0.0001734065,0.0003118619,0.00007793978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003097264,"about_ca_system_score_gemma":0.00008051901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002824029,"about_ca_topic_score_gemma":0.0001850938,"domain_scores_codex":[0.9987118,0.0001183613,0.0002886966,0.0002970252,0.000207515,0.0003766086],"domain_scores_gemma":[0.9994426,0.00003610011,0.00005142873,0.0002870321,0.00004558438,0.0001372218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000564109,0.0001477393,0.004687781,0.00003266756,0.000216213,0.000411728,0.002819505,0.0006231436,0.9763541,0.00008948629,0.002518579,0.01153498],"study_design_scores_gemma":[0.002785537,0.006258876,0.05597408,0.002476515,0.0003481407,0.01779743,0.007487662,0.004977078,0.3347157,0.001427364,0.5630938,0.002657873],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943474,0.00235875,0.0003450367,0.001331593,0.00111544,0.0001496324,0.00006925839,0.00001475221,0.0002681154],"genre_scores_gemma":[0.9973723,0.000467959,0.000144779,0.0006977547,0.0008612328,0.000006763492,0.00003168503,0.00002828585,0.0003892783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6416384,"threshold_uncertainty_score":0.5242728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01606494469308964,"score_gpt":0.2907757093106252,"score_spread":0.2747107646175355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}