{"id":"W4405107401","doi":"10.1182/blood-2024-212973","title":"Lack of Benefit of Autologous Hematopoietic Cell Transplantation (auto-HCT) in Mantle Cell Lymphoma (MCL) Patients (pts) in First Complete Remission (CR) with Undetectable Minimal Residual Disease (uMRD): Initial Report from the ECOG-ACRIN EA4151 Phase 3 Randomized Trial","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"","keywords":"Mantle cell lymphoma; Medicine; Minimal residual disease; Hematopoietic stem cell transplantation; Transplantation; Hematopoietic cell; Lymphoma; Internal medicine; Complete remission; Oncology; Surgery; Gastroenterology; Cancer research; Haematopoiesis; Stem cell; Chemotherapy; Leukemia; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002113639,0.0005517969,0.001391365,0.0001716462,0.0002117186,0.0009033887,0.0005191339,0.0009980039,0.002980964],"category_scores_gemma":[0.002123065,0.0002258666,0.001615433,0.0002573377,0.0006003111,0.0007139011,0.0003585872,0.002085274,0.0003791264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004751171,"about_ca_system_score_gemma":0.0004229078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003313292,"about_ca_topic_score_gemma":0.0007007745,"domain_scores_codex":[0.999252,0.0005001577,0.00005154786,0.00009901225,0.00004039869,0.00005680494],"domain_scores_gemma":[0.9984969,0.0006836768,0.0003131999,0.0001149898,0.00005184852,0.0003393437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9472071,0.002150843,0.00383938,0.0008952435,0.002669901,0.00007409987,0.00005948422,0.0006907806,0.002493362,0.0002132289,0.001030368,0.03867625],"study_design_scores_gemma":[0.7679351,0.206168,0.01683788,0.0001873401,0.003957239,0.0002348346,0.00005530901,0.001113885,0.0008323788,0.0009741973,0.001678871,0.00002498444],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895301,0.006710124,0.0003331579,0.000810803,0.0001995502,0.0004430441,0.0004764583,0.0000406251,0.001456121],"genre_scores_gemma":[0.9964153,0.00127447,0.0002376005,0.0008083969,0.0001446916,0.0002428883,0.0003550319,0.000005769467,0.00051589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002980964,"threshold_uncertainty_score":0.01117814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02012098563730711,"score_gpt":0.2763572375957675,"score_spread":0.2562362519584603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}