{"id":"W4405119441","doi":"10.1016/j.aohep.2024.101723","title":"P-109 ALKALINE PHOSPHATASE AND CIRRHOSIS AT DIAGNOSIS ARE ASSOCIATED WITH DEEP RESPONSE TO URSODEOXYCHOLIC ACID IN PRIMARY BILIARY CHOLANGITIS","year":2024,"lang":"en","type":"article","venue":"Annals of Hepatology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Ursodeoxycholic acid; Medicine; Primary biliary cirrhosis; Alkaline phosphatase; Gastroenterology; Internal medicine; Biliary cirrhosis; Cirrhosis; Biochemistry; Enzyme; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003105913,0.0002229698,0.0006136365,0.0003549706,0.00004223973,0.00001571149,0.00007229051,0.0001385525,0.000174644],"category_scores_gemma":[0.0002934458,0.0001781281,0.0001049198,0.0004690634,0.0001037069,0.00009726535,0.00009425446,0.0001281089,0.00004447553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001236924,"about_ca_system_score_gemma":0.0001024518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002968465,"about_ca_topic_score_gemma":0.000556897,"domain_scores_codex":[0.9984362,0.0001781611,0.0003211177,0.0004920729,0.0002087157,0.0003636959],"domain_scores_gemma":[0.9986512,0.0005812876,0.0000811318,0.000309697,0.00009549963,0.0002811941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00268495,0.001045105,0.9725277,0.0001702774,0.0005419277,0.003938651,0.000459934,0.000001490184,0.0002483565,0.00003576001,0.01192147,0.006424313],"study_design_scores_gemma":[0.001661305,0.001107298,0.9782799,0.000847073,0.0003008481,0.00008466875,0.00004506759,0.00004615041,0.01246828,0.00004444617,0.00493015,0.000184798],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9536542,0.03095348,0.00000139747,0.01420273,0.00006336578,0.0004980725,0.0004798549,0.00005667072,0.00009024389],"genre_scores_gemma":[0.9892014,0.004223646,0.00005645954,0.005757284,0.0000200246,0.0003456409,0.0002938123,0.00003386343,0.00006789624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03554719,"threshold_uncertainty_score":0.7263853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02912889911130082,"score_gpt":0.3022706391408648,"score_spread":0.273141740029564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}