{"id":"W4405181189","doi":"10.1158/1538-8514.cancerchem24-a001","title":"Abstract A001: Navigating the future of therapeutic development: innovations in safety and efficacy through advanced research methodologies and nanotechnology","year":2024,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Pharmacogenomics; Risk analysis (engineering); SAFER; Drug delivery; Computer science; Medicine; Nanotechnology; Pharmacology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002758346,0.0006611169,0.000359152,0.0008808211,0.001056029,0.005134009,0.0009358057,0.003330761,0.02957616],"category_scores_gemma":[0.002506778,0.0002684872,0.0005190048,0.000751894,0.001936444,0.003880235,0.002193464,0.003710907,0.00772753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001734208,"about_ca_system_score_gemma":0.003651793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000743973,"about_ca_topic_score_gemma":0.0006710796,"domain_scores_codex":[0.9986658,0.0004098975,0.00004580158,0.0001314259,0.0006505743,0.00009647181],"domain_scores_gemma":[0.9978666,0.0008303742,0.0001762526,0.000127851,0.0006933859,0.0003055233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001436608,0.0002105973,0.0006613975,0.001653028,0.00003313052,0.0003436539,0.0002801394,0.003445043,0.01646758,0.4977172,0.2260536,0.2529911],"study_design_scores_gemma":[0.00004031389,0.0002967209,0.0007200032,0.0007968938,0.00002260304,0.0004210951,0.0003151695,0.008482401,0.01030389,0.198464,0.7800852,0.00005165344],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.02087646,0.1265444,0.1544275,0.2243375,0.03372608,0.0004429144,0.000982128,0.001822099,0.436841],"genre_scores_gemma":[0.3236901,0.1826489,0.1628567,0.026801,0.0177664,0.0005167123,0.001180577,0.001010595,0.283529],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02957616,"threshold_uncertainty_score":0.0989421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1016947530827468,"score_gpt":0.4288803136813428,"score_spread":0.327185560598596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}