{"id":"W4405190744","doi":"10.3390/cancers16234111","title":"Aptamer’s Structure Optimization for Better Diagnosis and Treatment of Glial Tumors","year":2024,"lang":"en","type":"article","venue":"Cancers","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Science and Higher Education of the Russian Federation; Russian Science Foundation","keywords":"Aptamer; Computer science; Computational biology; Biology; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002255015,0.0003601759,0.0002092237,0.0001866984,0.0001202663,0.0002079763,0.0002295061,0.0003885123,0.0009369092],"category_scores_gemma":[0.0002419432,0.0001301308,0.000347631,0.0001372831,0.0001399122,0.0002096379,0.0001639882,0.00044441,0.000354388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003488037,"about_ca_system_score_gemma":0.000305328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004190561,"about_ca_topic_score_gemma":0.0006053916,"domain_scores_codex":[0.9998763,0.00002222772,0.000009978864,0.00003241908,0.0000387587,0.00002035708],"domain_scores_gemma":[0.9999343,0.00001265272,0.00002242336,0.000005655107,0.00001685575,0.000008209697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000131478,0.00006050935,0.0002291927,0.0001430643,0.00001395585,0.0001191054,0.00003502861,0.005455898,0.9801952,0.0006848181,0.0002931176,0.01263879],"study_design_scores_gemma":[0.00004390613,0.0005790245,0.0005748295,0.00001748363,0.00003547085,0.0003984214,0.00002064512,0.01892384,0.9698899,0.000374018,0.00912649,0.00001581014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8428511,0.01492671,0.1324788,0.0009665135,0.0002005163,0.0002012372,0.0002853278,0.000509509,0.007580224],"genre_scores_gemma":[0.948201,0.003686586,0.04496231,0.0003047077,0.0000268547,0.0001080294,0.0002597667,0.0000445851,0.0024061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009369092,"threshold_uncertainty_score":0.003134251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0102959643371616,"score_gpt":0.2805103390131443,"score_spread":0.2702143746759827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}