{"id":"W4405198875","doi":"10.1016/j.cris.2024.100103","title":"Exploring novel pyrethroid resistance mechanisms through RNA-seq in Triatoma dimidiata from Colombia","year":2024,"lang":"en","type":"article","venue":"Current Research in Insect Science","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Universidad de Antioquia","keywords":"Pyrethroid; Triatoma; Biology; Resistance (ecology); Hemiptera; Zoology; Reduviidae; Ecology; Pesticide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002844858,0.0002256757,0.0002240479,0.0004778228,0.0002574863,0.0002920954,0.001146925,0.0001172041,0.00002033714],"category_scores_gemma":[0.0005623439,0.0002204736,0.00007530591,0.00275392,0.0007679427,0.00008485578,0.0005673725,0.0007345736,0.00003163936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003065843,"about_ca_system_score_gemma":0.001215105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004531034,"about_ca_topic_score_gemma":0.002939264,"domain_scores_codex":[0.9959552,0.0001721799,0.0004267734,0.001225499,0.001126309,0.001094074],"domain_scores_gemma":[0.9987265,0.0001546501,0.0000429537,0.0007390694,0.0001874075,0.0001494149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001556849,0.0002076084,0.0003686358,0.000119596,0.000007169811,0.00003428657,0.0008814405,0.00004615347,0.9856002,0.007034072,0.0005406921,0.00500448],"study_design_scores_gemma":[0.001052415,0.0003601725,0.007549075,0.0009357604,0.000004895746,0.000003690519,0.000485323,0.0005930291,0.9314626,0.02341799,0.03359422,0.0005407823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826579,0.01185694,0.002106381,0.0002739823,0.001379449,0.000453093,0.00007037719,0.0000270878,0.001174804],"genre_scores_gemma":[0.9919453,0.005645131,0.001683227,0.00003086888,0.0002689031,0.0002374195,0.00003577392,0.00002791655,0.0001254202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05413754,"threshold_uncertainty_score":0.899065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3609979065193606,"score_gpt":0.4258382764097092,"score_spread":0.06484036989034858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}