{"id":"W4405228863","doi":"10.1093/mrcr/rxae070","title":"Macrophage migration inhibitory factor as a potential ‘missing important factor’ driving inflammatory arthritis in adrenocorticotropic hormone deficiency","year":2024,"lang":"en","type":"letter","venue":"Modern Rheumatology Case Reports","topic":"Macrophage Migration Inhibitory Factor","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kingston Health Sciences Centre; Queen's University","funders":"","keywords":"Macrophage migration inhibitory factor; Adrenocorticotropic hormone; Immunology; Medicine; Arthritis; Inhibitory postsynaptic potential; Macrophage; Endocrinology; Hormone; Internal medicine; Biology; Cytokine; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0004034763,0.001448833,0.002028151,0.001430664,0.0005401676,0.0002673358,0.0002723161,0.00434149,0.001432212],"category_scores_gemma":[0.0003919728,0.001493223,0.0006018371,0.0003531587,0.0006455448,0.000444199,0.0003810894,0.005192315,0.0006278749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006678136,"about_ca_system_score_gemma":0.001310042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001449825,"about_ca_topic_score_gemma":0.001331414,"domain_scores_codex":[0.9903259,0.0008831121,0.004262383,0.002421955,0.0003714223,0.001735256],"domain_scores_gemma":[0.9956949,0.0002756279,0.002180945,0.001475943,0.0002309924,0.0001416259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00005529621,0.0001519874,0.01024221,0.000707352,0.0003461906,0.7411095,0.00264616,0.00002191069,0.132029,0.00001229341,0.1085077,0.004170479],"study_design_scores_gemma":[0.001862555,0.0003528117,0.002027603,0.001596481,0.000274444,0.8929203,0.000234318,0.0003470713,0.01725244,0.00119466,0.07916714,0.002770156],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9236461,0.05904849,0.0006151384,0.007563041,0.006811826,0.001346943,0.0002726766,0.0006240573,0.0000717416],"genre_scores_gemma":[0.9895335,0.001027976,0.00006186008,0.00521364,0.0003411281,0.0002919749,0.001702284,0.0003005287,0.001527115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1518108,"threshold_uncertainty_score":0.9998261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007503935359905947,"score_gpt":0.2247824130261362,"score_spread":0.2172784776662303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}