{"id":"W4405231044","doi":"10.1016/j.jaccao.2024.09.014","title":"Cardiovascular Safety in Oncology Clinical Trials","year":2024,"lang":"fi","type":"review","venue":"JACC CardioOncology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Astellas Pharma; AstraZeneca; Pfizer","keywords":"Medicine; Clinical trial; Internal medicine; Clinical Oncology; Intensive care medicine; Oncology; Medical physics; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","metaepi_broad","research_integrity","insufficient_payload"],"consensus_categories":["metaresearch","metaepi_narrow","metaepi_broad","research_integrity"],"category_scores_codex":[0.07690708,0.001923303,0.03234966,0.001516222,0.0001719277,0.0000998828,0.0008596856,0.009932,0.0006232783],"category_scores_gemma":[0.01138884,0.00163533,0.02681225,0.002172092,0.0008828954,0.000160765,0.000591038,0.00847428,0.004007001],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.00723939,"about_ca_system_score_gemma":0.009522566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002035193,"about_ca_topic_score_gemma":0.0001556287,"domain_scores_codex":[0.9524571,0.03227373,0.008872128,0.003279753,0.001275111,0.001842122],"domain_scores_gemma":[0.9832621,0.0107091,0.001770422,0.002868251,0.000417424,0.0009727003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007284125,0.000443608,0.00006845462,0.0108968,0.02788055,0.005910117,0.0003778707,0.00003539335,0.00005282839,0.0004328278,0.01204136,0.9411318],"study_design_scores_gemma":[0.008682174,0.001688833,0.0001707499,0.009229117,0.04695391,0.003275788,0.0004008175,0.00003521422,0.00004505243,0.0001443275,0.9281705,0.001203502],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002708599,0.9001308,0.0003700718,0.002142186,0.02103855,0.007959137,0.0003672266,0.0002316848,0.0674895],"genre_scores_gemma":[0.002245826,0.9685593,0.0002929325,0.001495068,0.02137065,0.00102622,0.0007864646,0.0003809778,0.003842528],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9399283,"threshold_uncertainty_score":0.9993511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2959487604358577,"score_gpt":0.5190284124629171,"score_spread":0.2230796520270594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}