{"id":"W4405231044","doi":"10.1016/j.jaccao.2024.09.014","title":"Cardiovascular Safety in Oncology Clinical Trials","year":2024,"lang":"fi","type":"review","venue":"JACC CardioOncology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Astellas Pharma; AstraZeneca; Pfizer","keywords":"Medicine; Clinical trial; Internal medicine; Clinical Oncology; Intensive care medicine; Oncology; Medical physics; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05937904,0.0009595316,0.003817929,0.003562035,0.000757166,0.004157231,0.002080705,0.004790821,0.00818532],"category_scores_gemma":[0.1296807,0.0008892447,0.002761944,0.004192187,0.002477932,0.002959416,0.001968096,0.00664953,0.001908133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002509231,"about_ca_system_score_gemma":0.00933262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001136982,"about_ca_topic_score_gemma":0.001381559,"domain_scores_codex":[0.9381581,0.04152261,0.01015991,0.001704032,0.007908328,0.0005469694],"domain_scores_gemma":[0.7636744,0.1950123,0.02193673,0.004791872,0.01293498,0.001649725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004805344,0.00007259524,0.000441394,0.09529562,0.0008493292,0.0001041886,0.0003226426,0.0005850476,0.0002992737,0.01806397,0.05819544,0.82529],"study_design_scores_gemma":[0.0007917141,0.0005787362,0.002521373,0.2166892,0.001358723,0.0006735974,0.0002235088,0.0006296625,0.0006427162,0.02956287,0.7462558,0.00007212631],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002054127,0.9868115,0.002021351,0.005010937,0.001514354,0.0002995423,0.000160229,0.00004685956,0.003929826],"genre_scores_gemma":[0.01016744,0.969304,0.006925859,0.007407318,0.00321545,0.001276191,0.0003974736,0.0000367283,0.001269503],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.05937904,"threshold_uncertainty_score":0.3140301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2959487604358577,"score_gpt":0.5190284124629171,"score_spread":0.2230796520270594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}