{"id":"W4405245917","doi":"10.1080/08880018.2024.2437047","title":"Safety and Tolerability of a 3-Day Fosaprepitant Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients: Results of an Open-Label, Single-Arm Phase 4 Trial","year":2024,"lang":"en","type":"article","venue":"Pediatric Hematology and Oncology","topic":"Nausea and vomiting management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Anglo American (Canada)","funders":"","keywords":"Medicine; Tolerability; Nausea; Discontinuation; Regimen; Antiemetic; Vomiting; Adverse effect; Internal medicine; Chemotherapy; Chemotherapy regimen; Aprepitant; Chemotherapy-induced nausea and vomiting","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002019059,0.001045243,0.001836626,0.0002516254,0.0002956376,0.0006698968,0.0007142039,0.001083088,0.001973844],"category_scores_gemma":[0.001600817,0.0004448517,0.001455875,0.0003153693,0.000901924,0.0009890595,0.0002157039,0.002667724,0.0003798648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006970689,"about_ca_system_score_gemma":0.001273151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004955459,"about_ca_topic_score_gemma":0.001412467,"domain_scores_codex":[0.999332,0.000404895,0.00004064407,0.00007764862,0.00007186319,0.0000729625],"domain_scores_gemma":[0.9986291,0.0003585099,0.0003993636,0.00009780331,0.0001022055,0.000412939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7882352,0.05751624,0.007765506,0.001421949,0.001717237,0.0003451038,0.0003977955,0.001973588,0.02679721,0.0002050538,0.002383933,0.1112413],"study_design_scores_gemma":[0.485432,0.4924827,0.01679771,0.00005851187,0.0003968927,0.0002974053,0.00005667413,0.001086212,0.002079049,0.0001145973,0.001172692,0.00002560049],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953668,0.00207303,0.0002970953,0.0001828645,0.00005319122,0.001034463,0.0004355326,0.00003490349,0.0005221721],"genre_scores_gemma":[0.9915923,0.00260384,0.001898946,0.0005878326,0.0001680176,0.001547027,0.001029987,0.00002421539,0.0005478878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002019059,"threshold_uncertainty_score":0.01067793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05335204666219206,"score_gpt":0.3773440394531746,"score_spread":0.3239919927909825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}