{"id":"W4405245917","doi":"10.1080/08880018.2024.2437047","title":"Safety and Tolerability of a 3-Day Fosaprepitant Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients: Results of an Open-Label, Single-Arm Phase 4 Trial","year":2024,"lang":"en","type":"article","venue":"Pediatric Hematology and Oncology","topic":"Nausea and vomiting management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Anglo American (Canada)","funders":"","keywords":"Medicine; Tolerability; Nausea; Discontinuation; Regimen; Antiemetic; Vomiting; Adverse effect; Internal medicine; Chemotherapy; Chemotherapy regimen; Aprepitant; Chemotherapy-induced nausea and vomiting","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002609596,0.0001470475,0.0008124746,0.0002382957,0.00005693686,0.000009413163,0.0001090198,0.0002157616,0.00000480075],"category_scores_gemma":[0.001112461,0.0001099795,0.00003700781,0.000300537,0.0001331524,0.0001065168,0.0001358511,0.0001687903,9.593957e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004515778,"about_ca_system_score_gemma":0.0001867925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003787418,"about_ca_topic_score_gemma":0.00004918098,"domain_scores_codex":[0.9978806,0.0003012658,0.001078013,0.0004184205,0.0001096551,0.0002120502],"domain_scores_gemma":[0.9968454,0.00227063,0.0004766794,0.0002232266,0.0001152595,0.00006877961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3776296,0.03982679,0.1334629,0.01417572,0.0007898921,0.0000852122,0.01127111,0.000003174841,0.002417523,0.007461165,0.0009210719,0.4119558],"study_design_scores_gemma":[0.7694456,0.1282866,0.07622776,0.0003939959,0.004371769,0.0001181397,0.001366404,0.004478372,0.005734732,0.007019693,0.001856168,0.0007007566],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942204,0.001781199,0.0001632435,0.0009413031,0.0001892269,0.002445045,0.00003332655,0.00001405744,0.0002122076],"genre_scores_gemma":[0.9979005,0.0009681426,0.0008108532,0.00004391508,0.0001519967,0.00006768027,0.00002063682,0.00001380016,0.00002244718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.411255,"threshold_uncertainty_score":0.4484833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05335204666219206,"score_gpt":0.3773440394531746,"score_spread":0.3239919927909825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}