{"id":"W4405289337","doi":"10.14740/wjon1960","title":"Causal Relationships Between Gut Microbiota, Immune Cell and Pancreatic Cancer: A Two-Step, Two-Sample Mendelian Randomization Study","year":2024,"lang":"en","type":"article","venue":"World Journal of Oncology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Mendelian randomization; Medicine; Immune system; Pancreatic cancer; Mendelian inheritance; Cancer; Randomization; Oncology; Immunology; Internal medicine; Bioinformatics; Genetics; Clinical trial; Gene; Biology; Genotype","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03275532,0.001610475,0.002210066,0.0009688239,0.0009033521,0.0009695594,0.001944917,0.001914483,0.005161107],"category_scores_gemma":[0.04489562,0.0007023581,0.003949381,0.0008790871,0.001364655,0.0007037635,0.0009972996,0.001375778,0.0003067524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006146603,"about_ca_system_score_gemma":0.001404933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001798175,"about_ca_topic_score_gemma":0.001145829,"domain_scores_codex":[0.9560149,0.03521479,0.001093085,0.004969975,0.001664671,0.001042613],"domain_scores_gemma":[0.9733594,0.01792072,0.002626662,0.005024976,0.0006545306,0.0004136619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1051074,0.005972367,0.686722,0.003173952,0.04202415,0.008236043,0.002916946,0.009472249,0.01970946,0.03116859,0.004244759,0.08125205],"study_design_scores_gemma":[0.03172354,0.09202401,0.4820513,0.0007185423,0.06639351,0.01611202,0.002058942,0.242515,0.01332961,0.03758457,0.0149314,0.0005576706],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8853765,0.001503303,0.1075884,0.0005900553,0.0002918034,0.002626931,0.0008156765,0.0002312385,0.0009759935],"genre_scores_gemma":[0.9573444,0.0001923089,0.03882989,0.0002684447,0.0000586781,0.002036319,0.0003137805,0.00002955984,0.0009266434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03275532,"threshold_uncertainty_score":0.1732288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02236793333395953,"score_gpt":0.3295059943620058,"score_spread":0.3071380610280462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}