{"id":"W4405332658","doi":"10.1002/smsc.202400471","title":"Site‐Specific Disulfide‐Mediated Crosslinking of DNA Nanocubes for Enhanced Biological Applications","year":2024,"lang":"en","type":"article","venue":"Small Science","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Nanotechnology; DNA; Nucleic acid; Nanomaterials; Endocytosis; DNA origami; Biophysics; Chemistry; Nanostructure; Materials science; Combinatorial chemistry; Cell; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000361943,0.0001009989,0.0001138826,0.0000735045,0.0001508017,0.00005425644,0.0002618745,0.00008750143,0.000001492517],"category_scores_gemma":[0.0001086498,0.00007469944,0.00009570164,0.0004728682,0.000668044,0.000004563003,0.00009440303,0.00004616116,0.000003246768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001525958,"about_ca_system_score_gemma":0.00007634655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002230435,"about_ca_topic_score_gemma":0.00001130153,"domain_scores_codex":[0.9989777,0.00001153262,0.0001928755,0.0004891116,0.0001039191,0.000224927],"domain_scores_gemma":[0.9994367,0.00004369349,0.00005257831,0.0002566795,0.0001585103,0.0000518318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001178092,0.00001984528,0.00007733065,0.00001208632,0.000005592118,2.505055e-7,0.00001653972,0.000002587853,0.9905908,0.000577076,0.00004735918,0.008638779],"study_design_scores_gemma":[0.00005057288,0.0001135701,0.0001699568,0.00002110971,0.000006181412,0.00000204979,0.00002474739,0.0001024042,0.9718534,0.000620758,0.02692514,0.0001101627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8710243,0.0007837234,0.1272474,0.00008203149,0.00006671147,0.0002589254,0.00005516691,0.00007208459,0.0004096761],"genre_scores_gemma":[0.9814281,0.0002900246,0.01785714,0.0000448065,0.0001108341,0.00004789639,0.00007846488,0.000007218408,0.0001354776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1104038,"threshold_uncertainty_score":0.3046155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02066862841276974,"score_gpt":0.302616459666004,"score_spread":0.2819478312532343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}