{"id":"W4405332658","doi":"10.1002/smsc.202400471","title":"Site‐Specific Disulfide‐Mediated Crosslinking of DNA Nanocubes for Enhanced Biological Applications","year":2024,"lang":"en","type":"article","venue":"Small Science","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Nanotechnology; DNA; Nucleic acid; Nanomaterials; Endocytosis; DNA origami; Biophysics; Chemistry; Nanostructure; Materials science; Combinatorial chemistry; Cell; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001254009,0.0002280263,0.0001523664,0.0001091943,0.0001149811,0.0001233309,0.000200101,0.0002085142,0.0008163319],"category_scores_gemma":[0.0001599536,0.0001286726,0.0001410814,0.00009356915,0.0001101281,0.000150721,0.0001712525,0.0002773209,0.0002481503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003345276,"about_ca_system_score_gemma":0.0002920233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007981137,"about_ca_topic_score_gemma":0.002270109,"domain_scores_codex":[0.9999071,0.000009794804,0.000008083601,0.00002746796,0.00003451015,0.00001295881],"domain_scores_gemma":[0.9999192,0.00001553755,0.00001915282,0.00001105657,0.00002166439,0.00001336976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008933342,0.000005471247,0.00002518788,0.00001780972,0.000001154245,0.00001504921,0.00001107372,0.0001051266,0.9984535,0.0001005695,0.00004202653,0.001214017],"study_design_scores_gemma":[0.000002273905,0.00003298176,0.000160716,0.00000129468,0.000001467056,0.00003281275,0.000004588936,0.001064528,0.9974858,0.00002299384,0.001188898,0.000001697662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9512079,0.002508756,0.04050789,0.0002287511,0.0001585264,0.000107267,0.0003147275,0.0002792371,0.004686987],"genre_scores_gemma":[0.9542524,0.00122795,0.03902857,0.00009623567,0.00001604869,0.00006751777,0.0002409179,0.00007232658,0.004997927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008163319,"threshold_uncertainty_score":0.002730966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02066862841276974,"score_gpt":0.302616459666004,"score_spread":0.2819478312532343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}