{"id":"W4405350059","doi":"10.1111/jcmm.70290","title":"Regulation of Clusterin in the Heart and Plasma of Mice After Transverse Aortic Constriction","year":2024,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Alliance Nationale pour les Sciences de la Vie et de la Santé; Österreichische Agentur für Internationale Mobilität und Kooperation in Bildung, Wissenschaft und Forschung; Providence Health Care","keywords":"Clusterin; Pressure overload; Internal medicine; Ventricular remodeling; Heart failure; Cardiology; Medicine; Ejection fraction; Muscle hypertrophy; Fibrosis; Myocardial infarction; Cardiac fibrosis; Endocrinology; Biology; Apoptosis; Cardiac hypertrophy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005042569,0.00007592205,0.0002942237,0.0002432031,0.000007067293,0.000002964041,0.00002949945,0.0000564366,0.00003415917],"category_scores_gemma":[0.00007622902,0.00004838589,0.00006060677,0.0001536322,0.0002073286,0.00003609182,0.00001065624,0.0001516694,1.977574e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001262495,"about_ca_system_score_gemma":0.00004331883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009234836,"about_ca_topic_score_gemma":0.000001277536,"domain_scores_codex":[0.9990564,0.00009629939,0.0004509541,0.00008513894,0.0002383964,0.00007281083],"domain_scores_gemma":[0.999597,0.00008637309,0.00009905053,0.00009091286,0.00006840219,0.00005826206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005326628,0.00004656753,0.00102015,0.0006203578,0.00004566173,0.0004995649,0.001481041,0.0000125676,0.9939922,0.00006215464,0.00007636096,0.001610692],"study_design_scores_gemma":[0.02287079,0.01005821,0.4277409,0.01208991,0.005517295,0.0222813,0.007357834,0.01942945,0.4632058,0.001680976,0.00729273,0.0004748522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854792,0.007966412,0.003314791,0.002804869,0.0001401295,0.0001525004,0.000001848008,0.000002144973,0.0001380543],"genre_scores_gemma":[0.9991992,0.0002956816,0.000240859,0.0001783669,0.00006110247,0.000001704947,0.000002208857,0.000007438884,0.00001351296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5307865,"threshold_uncertainty_score":0.1973119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008853003352311425,"score_gpt":0.2615618527251487,"score_spread":0.2527088493728373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}