{"id":"W4405356226","doi":"10.1016/j.mucimm.2024.12.005","title":"How the early life microbiome shapes immune programming in childhood asthma and allergies","year":2024,"lang":"en","type":"review","venue":"Mucosal Immunology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Microbiome; Allergy; Asthma; Immunology; Immune system; Medicine; Hygiene hypothesis; Biology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000674087,0.0008020293,0.001337351,0.0009008264,0.0001824261,0.001230441,0.0006885385,0.001355125,0.003092343],"category_scores_gemma":[0.0011112,0.0002048145,0.0003860809,0.001345178,0.0004525328,0.0009579947,0.0008860527,0.002007456,0.001319586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007107632,"about_ca_system_score_gemma":0.001390506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001900761,"about_ca_topic_score_gemma":0.003378866,"domain_scores_codex":[0.9998482,0.00003210723,0.00001636234,0.00003423017,0.00004969121,0.00001936099],"domain_scores_gemma":[0.9996129,0.0002046603,0.00004351593,0.0000102788,0.00007993865,0.00004880856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001371012,0.00003996595,0.0003513683,0.00997627,0.0001435304,0.000120467,0.00003472342,0.0003175378,0.001296467,0.003933308,0.04262495,0.9410242],"study_design_scores_gemma":[0.00003386889,0.00008551926,0.003061754,0.006434322,0.0002572559,0.0005698659,0.00007379291,0.0001301794,0.0004169532,0.003974386,0.9849294,0.00003277299],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006910253,0.9987159,0.00008575656,0.0004160079,0.0002769383,0.000001484489,0.0000221309,0.00000408005,0.0004087715],"genre_scores_gemma":[0.0003769455,0.9986701,0.000101951,0.0002045159,0.0002954588,0.000003409058,0.00002408222,0.000001071205,0.0003224656],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003092343,"threshold_uncertainty_score":0.01034492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01676210812342476,"score_gpt":0.2745469409581586,"score_spread":0.2577848328347338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}