{"id":"W4405387458","doi":"10.1111/all.16420","title":"Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy","year":2024,"lang":"en","type":"article","venue":"Allergy","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Allergy Therapeutics; Astellas Pharma; Mylan; Immune Tolerance Network; Horizon Pharma; Genentech; Grifols; Valeant Pharmaceuticals International; Baxalta; Aimmune Therapeutics; Eli Lilly and Company; AstraZeneca; CSL Behring; Regeneron Pharmaceuticals; Teva Pharmaceutical Industries; Sanofi; GlaxoSmithKline; Food Allergy Research and Education; National Heart, Lung, and Blood Institute; Pfizer; National Institute of Allergy and Infectious Diseases; Celgene","keywords":"Oral immunotherapy; Dupilumab; Peanut allergy; Medicine; Allergy; Immunotherapy; Food allergy; Adjunct; Immunology; Anaphylaxis; Dermatology; Asthma; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001957097,0.0002726029,0.0003249467,0.000621493,0.00007018719,0.00007535214,0.0002428926,0.0001243951,0.001324757],"category_scores_gemma":[0.00004042116,0.000207755,0.00009324357,0.001030626,0.00004567148,0.0002208456,0.00007027837,0.0003929678,0.0004546509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000108137,"about_ca_system_score_gemma":0.0003018193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006022117,"about_ca_topic_score_gemma":0.002013289,"domain_scores_codex":[0.9977704,0.00008701608,0.0002957016,0.0005920324,0.0006712123,0.0005836338],"domain_scores_gemma":[0.9989914,0.00005064229,0.00002508872,0.0004555513,0.0001340963,0.0003432724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.03745278,0.01497303,0.1076496,0.001173571,0.005385064,0.008160056,0.01431686,0.001504381,0.003716042,0.02642217,0.09076642,0.68848],"study_design_scores_gemma":[0.006169075,0.009874179,0.4971894,0.0002127178,0.000007009092,0.00002290755,0.0001786013,0.0004144723,0.0001811772,0.0002857944,0.4848548,0.0006098509],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871877,0.001687864,0.00002907899,0.001337985,0.0002278819,0.0004020181,0.000006803748,0.0001270397,0.00899357],"genre_scores_gemma":[0.9937415,0.0007977738,0.0002906724,0.0009093893,0.0002942711,0.00006362388,0.0001485924,0.0000820179,0.00367215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6878701,"threshold_uncertainty_score":0.9995882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194098955539367,"score_gpt":0.2867347447865287,"score_spread":0.274793755231135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}