{"id":"W4405387458","doi":"10.1111/all.16420","title":"Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy","year":2024,"lang":"en","type":"article","venue":"Allergy","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Allergy Therapeutics; Astellas Pharma; Mylan; Immune Tolerance Network; Horizon Pharma; Genentech; Grifols; Valeant Pharmaceuticals International; Baxalta; Aimmune Therapeutics; Eli Lilly and Company; AstraZeneca; CSL Behring; Regeneron Pharmaceuticals; Teva Pharmaceutical Industries; Sanofi; GlaxoSmithKline; Food Allergy Research and Education; National Heart, Lung, and Blood Institute; Pfizer; National Institute of Allergy and Infectious Diseases; Celgene","keywords":"Oral immunotherapy; Dupilumab; Peanut allergy; Medicine; Allergy; Immunotherapy; Food allergy; Adjunct; Immunology; Anaphylaxis; Dermatology; Asthma; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000756061,0.0003274223,0.001082771,0.0001397261,0.0001823049,0.0003270523,0.0002514357,0.0002763041,0.001331678],"category_scores_gemma":[0.0009589219,0.0001529845,0.0004308533,0.0002430979,0.0002574636,0.0002423853,0.000229707,0.0008081437,0.000144335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004012562,"about_ca_system_score_gemma":0.0008479971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005997299,"about_ca_topic_score_gemma":0.001719093,"domain_scores_codex":[0.9997109,0.0001549112,0.00002378741,0.00003572654,0.00003491628,0.00003969709],"domain_scores_gemma":[0.9994299,0.0002043777,0.000178941,0.00001916043,0.000030594,0.0001370151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3143715,0.008788448,0.1740529,0.002996247,0.001500333,0.001877659,0.0004446119,0.001923373,0.02358503,0.0003627703,0.004259968,0.4658374],"study_design_scores_gemma":[0.1434088,0.4731606,0.339645,0.0005501303,0.003305275,0.006178785,0.0005246185,0.003755595,0.01148794,0.0002742746,0.01766092,0.00004813864],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888011,0.009620394,0.0001702275,0.0002209163,0.00004386138,0.0001790557,0.000187415,0.00001764541,0.000759353],"genre_scores_gemma":[0.994856,0.003419677,0.0009045714,0.000204739,0.00008665585,0.0001636787,0.0002097737,0.000003367066,0.0001514779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001331678,"threshold_uncertainty_score":0.004454911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194098955539367,"score_gpt":0.2867347447865287,"score_spread":0.274793755231135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}