{"id":"W4405436978","doi":"10.1016/s1470-2045(24)00640-5","title":"The landscape of primary mismatch repair deficient gliomas in children, adolescents, and young adults: a multi-cohort study","year":2024,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; Sunnybrook Health Science Centre; Sinai Health System; Princess Margaret Cancer Centre; University of Toronto; University Health Network; SickKids Foundation; Stollery Children's Hospital; Hospital for Sick Children","funders":"Stand Up To Cancer; Canadian Institutes of Health Research; American Lebanese Syrian Associated Charities; Children’s Oncology Group; V Foundation for Cancer Research; Department of Science and Technology, Ministry of Science and Technology, India; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Cohort; Medicine; Gerontology; Psychology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005598406,0.0003065147,0.0004974491,0.0006085328,0.0007370888,0.0009920052,0.0005445892,0.0006051142,0.001593391],"category_scores_gemma":[0.001826726,0.000444984,0.0007236645,0.001496088,0.0002448376,0.0008729745,0.0008946378,0.0009948626,0.000238411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000532538,"about_ca_system_score_gemma":0.0005604465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03106998,"about_ca_topic_score_gemma":0.03666126,"domain_scores_codex":[0.9994624,0.00009499971,0.00004302923,0.0002132633,0.00005160914,0.0001346792],"domain_scores_gemma":[0.9989886,0.00009787137,0.0003945096,0.0001266028,0.0001395802,0.0002528708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009498142,0.00001674352,0.9978986,0.0000143923,0.0002006045,0.0001024413,0.0002415468,0.00002040656,0.0002100794,0.00005604171,0.0003152119,0.000828886],"study_design_scores_gemma":[0.00000497916,0.0000508876,0.9984826,0.00001476487,0.00009534839,0.0002657622,0.0006064303,0.00004143913,0.00002431492,0.00003935969,0.0003681178,0.000005879896],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965841,0.0008373522,0.0001232869,0.0001931311,0.00001517178,0.000009809381,0.001873984,0.000003625068,0.0003594762],"genre_scores_gemma":[0.9982224,0.0004905556,0.00009005862,0.00008443926,0.00001146733,0.0000153063,0.0008340511,0.000005991407,0.0002457493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03106998,"threshold_uncertainty_score":0.06177831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01809468824186251,"score_gpt":0.2981594577119601,"score_spread":0.2800647694700976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}