{"id":"W4405452914","doi":"10.1111/all.16436","title":"The Bronchodilator and Anti‐Inflammatory Effect of Long‐Acting Muscarinic Antagonists in Asthma: An <scp>EAACI</scp> Position Paper","year":2024,"lang":"en","type":"review","venue":"Allergy","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Medical Research Council; Allergopharma; European Academy of Allergy and Clinical Immunology; Ministerio de Ciencia e Innovación; Moderna; Regeneron Pharmaceuticals; Immune Tolerance Network; Sanofi; GlaxoSmithKline; AstraZeneca; Allergy Therapeutics; Pfizer","keywords":"Medicine; Asthma; Bronchodilator; Muscarinic acetylcholine receptor; Lama; Bronchodilation; Bronchodilator Agents; Immunology; Pharmacology; Internal medicine; Receptor; COPD","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005842721,0.0005319543,0.00151402,0.0002288882,0.0001353504,0.00007014144,0.0001882774,0.0004127101,0.00001395467],"category_scores_gemma":[0.0001998143,0.0003088697,0.0004898854,0.0002695831,0.0001987609,0.0001396406,0.0001374139,0.0006183918,0.000033492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001056784,"about_ca_system_score_gemma":0.0003893898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002274018,"about_ca_topic_score_gemma":0.00006706563,"domain_scores_codex":[0.9973918,0.0004791774,0.0007894551,0.0005851063,0.000349341,0.0004051229],"domain_scores_gemma":[0.9981036,0.0007121589,0.000335898,0.0005557628,0.00004933313,0.0002432945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002842424,0.00007532689,0.0005817377,0.0216932,0.000436047,0.0007084034,0.0001016592,8.068023e-7,0.0000426331,0.00006422814,0.0004935788,0.9757739],"study_design_scores_gemma":[0.000638488,0.0005654603,0.005562278,0.01425951,0.0008011546,0.0002711019,0.00006642236,0.00001106506,0.00003136203,0.00000510404,0.9776307,0.0001573342],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04208529,0.9558887,9.843894e-7,0.00001828089,0.0003710701,0.0008374787,0.00002385639,0.00006560695,0.000708747],"genre_scores_gemma":[0.01205848,0.9867686,0.000007032194,0.00005584047,0.0004803429,0.00009731628,0.0001334616,0.0001119002,0.0002870244],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9771371,"threshold_uncertainty_score":0.9999363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01185069669588229,"score_gpt":0.3062528525551941,"score_spread":0.2944021558593118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}