{"id":"W4405452914","doi":"10.1111/all.16436","title":"The Bronchodilator and Anti‐Inflammatory Effect of Long‐Acting Muscarinic Antagonists in Asthma: An <scp>EAACI</scp> Position Paper","year":2024,"lang":"en","type":"review","venue":"Allergy","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Medical Research Council; Allergopharma; European Academy of Allergy and Clinical Immunology; Ministerio de Ciencia e Innovación; Moderna; Regeneron Pharmaceuticals; Immune Tolerance Network; Sanofi; GlaxoSmithKline; AstraZeneca; Allergy Therapeutics; Pfizer","keywords":"Medicine; Asthma; Bronchodilator; Muscarinic acetylcholine receptor; Lama; Bronchodilation; Bronchodilator Agents; Immunology; Pharmacology; Internal medicine; Receptor; COPD","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007407265,0.0009152688,0.001145044,0.001673293,0.0003099748,0.001320839,0.0008751604,0.001616614,0.01276069],"category_scores_gemma":[0.0008410753,0.0002058711,0.0009156949,0.001877143,0.0002778526,0.00135115,0.0008458215,0.002140581,0.005293912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006889497,"about_ca_system_score_gemma":0.001724185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001569098,"about_ca_topic_score_gemma":0.003493048,"domain_scores_codex":[0.999683,0.00005138041,0.00003769115,0.00003927896,0.0001562501,0.00003243323],"domain_scores_gemma":[0.9995847,0.0001340071,0.00008340794,0.000009374833,0.0001432854,0.00004527853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000152234,0.0000632329,0.00006783071,0.0299414,0.0001336231,0.0001425931,0.00004867874,0.0001305671,0.001930932,0.002011769,0.2713557,0.6940215],"study_design_scores_gemma":[0.000047028,0.0001000438,0.0004036477,0.007380488,0.000144398,0.0003280171,0.0000224839,0.00004494913,0.0002748693,0.0007137173,0.9905295,0.00001099842],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0001226404,0.9894173,0.00007710329,0.002039292,0.004843312,0.00002152628,0.00008065366,0.00001379037,0.003384355],"genre_scores_gemma":[0.0006922817,0.9886946,0.0001674111,0.00267574,0.002610426,0.00002495704,0.0001452072,0.000006363338,0.004983069],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01276069,"threshold_uncertainty_score":0.04268879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01185069669588229,"score_gpt":0.3062528525551941,"score_spread":0.2944021558593118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}