{"id":"W4405466985","doi":"10.1016/s0140-6736(24)02262-1","title":"Guselkumab in the IL-23 inhibition landscape for ulcerative colitis","year":2024,"lang":"en","type":"letter","venue":"The Lancet","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Ulcerative colitis; Interleukin 23; Medicine; Colitis; Immunology; Interleukin; Internal medicine; Disease; Cytokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002259498,0.0008039377,0.001450345,0.0005568343,0.001465089,0.002212597,0.000852708,0.02027955,0.004807405],"category_scores_gemma":[0.007834837,0.0004606434,0.001027788,0.0004137395,0.002262146,0.002559275,0.001017312,0.02191804,0.004585391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002732519,"about_ca_system_score_gemma":0.001735193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001675335,"about_ca_topic_score_gemma":0.003578365,"domain_scores_codex":[0.9983885,0.0005723655,0.0001482067,0.0001520405,0.0005176995,0.000221153],"domain_scores_gemma":[0.9973856,0.001554086,0.0001821959,0.0000751215,0.0003069331,0.0004961723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006539861,0.00008521761,0.0004060115,0.0001720588,0.00004924722,0.001772129,0.00005038817,0.0001494951,0.0005860751,0.004705383,0.9507022,0.04066788],"study_design_scores_gemma":[0.001124677,0.0003420404,0.001387822,0.000475892,0.0000722873,0.001827654,0.0001261599,0.0005312028,0.0004086674,0.02242446,0.9712138,0.00006529094],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00072317,0.02909495,0.0001779342,0.9245946,0.04088157,0.00001668281,0.00007381231,0.00004934519,0.004388011],"genre_scores_gemma":[0.01286056,0.01840726,0.0004255445,0.8228406,0.1343641,0.00008815388,0.00005412018,0.00004384558,0.01091578],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02027955,"threshold_uncertainty_score":0.01982588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01635706924338537,"score_gpt":0.2603862989200209,"score_spread":0.2440292296766355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}