{"id":"W4405467477","doi":"10.1016/j.microc.2024.112505","title":"On-line aptamer affinity solid-phase extraction capillary electrophoresis-mass spectrometry for the determination of SARS-CoV-2 nucleocapsid protein","year":2024,"lang":"en","type":"article","venue":"Microchemical Journal","topic":"SARS-CoV-2 detection and testing","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Aptamer; Capillary electrophoresis; Mass spectrometry; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Chromatography; Chemistry; Solid phase extraction; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Extraction (chemistry); Analytical Chemistry (journal); Virology; Molecular biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004950147,0.0002120969,0.0003043791,0.0002863395,0.0001725725,0.00008825758,0.0001294148,0.0001652579,0.00003897095],"category_scores_gemma":[0.0007810853,0.0001516201,0.0003058985,0.0004031868,0.00009363025,0.0001035625,0.00001815878,0.0009411097,0.00001950812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002363584,"about_ca_system_score_gemma":0.0001596827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005913898,"about_ca_topic_score_gemma":0.000001646462,"domain_scores_codex":[0.9984782,0.00004688833,0.0005308816,0.0002723201,0.0003369352,0.0003347348],"domain_scores_gemma":[0.9988518,0.000453681,0.0002087649,0.0001895486,0.0002367778,0.00005944171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000804739,0.0002639661,0.000003540453,0.0001280165,0.00009967598,0.0000738716,0.00005475695,5.884815e-7,0.9834279,0.00003617145,0.001205483,0.01390133],"study_design_scores_gemma":[0.001577062,0.001020186,0.000008777172,0.0003413607,0.0001875468,0.001851012,0.00005120138,0.006898561,0.9843192,0.001150487,0.002447384,0.0001472943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9277319,0.001254549,0.06925831,0.0007503727,0.0002875332,0.0004722779,0.000008728396,0.00007902473,0.000157317],"genre_scores_gemma":[0.9899755,0.0000595199,0.008397975,0.0006184232,0.0008245802,0.0000263958,0.000007010599,0.0000493643,0.00004126995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06224357,"threshold_uncertainty_score":0.6182887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04683748030123113,"score_gpt":0.3846078214206229,"score_spread":0.3377703411193917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}