{"id":"W4405481269","doi":"10.3389/fimmu.2024.1468957","title":"Hidden features: CD36/SR-B2, a master regulator of macrophage phenotype/function through metabolism","year":2024,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"CD36; Phenotype; Biology; Macrophage; Transcriptome; Cell biology; Lipid metabolism; Scavenger receptor; Function (biology); Gene expression; Receptor; Genetics; Gene; Biochemistry; In vitro; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002934433,0.0004984442,0.0007305496,0.0009323891,0.000197381,0.0009163212,0.0005035376,0.0007645543,0.005749383],"category_scores_gemma":[0.00044939,0.0001310119,0.0002772041,0.0009971453,0.0003012033,0.0009717792,0.0004987134,0.001476384,0.003823129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004977998,"about_ca_system_score_gemma":0.0007181218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005100523,"about_ca_topic_score_gemma":0.000743996,"domain_scores_codex":[0.9998945,0.0000139206,0.0000120102,0.00002251491,0.00004148573,0.00001559323],"domain_scores_gemma":[0.9998758,0.00003479203,0.0000167182,0.000004838705,0.00004362504,0.00002430551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001825824,0.00003800587,0.0002189092,0.01287478,0.00005919454,0.0002489345,0.00006137105,0.0002942099,0.01101419,0.008869059,0.08582488,0.8803138],"study_design_scores_gemma":[0.000008093488,0.00005531154,0.0004950901,0.001009092,0.0000342891,0.0007076171,0.00003012914,0.00005882652,0.0009936101,0.001788046,0.9948107,0.000009199435],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003380275,0.9932557,0.0003871127,0.001077575,0.001409963,0.000006233059,0.00008939269,0.00003125927,0.003404583],"genre_scores_gemma":[0.002422069,0.9910451,0.0003084178,0.00077665,0.0009997437,0.000008692419,0.000188514,0.000005567187,0.004245259],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005749383,"threshold_uncertainty_score":0.01923358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01722889284388292,"score_gpt":0.2648062571366457,"score_spread":0.2475773642927628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}