{"id":"W4405485646","doi":"10.1016/j.biopha.2024.117755","title":"A novel serous ovarian carcinoma model induced by DMBA: Results from OncoTherad® (MRB-CFI-1) immunotherapy preclinical testing","year":2024,"lang":"en","type":"article","venue":"Biomedicine & Pharmacotherapy","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo; Michael Smith Health Research BC","keywords":"Ovarian carcinoma; DMBA; Serous fluid; Medicine; Immunotherapy; Oncology; Cancer research; Internal medicine; Ovarian cancer; Cancer; Carcinogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002216388,0.0004411821,0.0002802422,0.0004894604,0.0001395838,0.0001854739,0.0001357975,0.0002278955,0.001486495],"category_scores_gemma":[0.0001271023,0.0001036398,0.000288244,0.000193401,0.0002480907,0.0001990195,0.0001559444,0.0005705539,0.0002661747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001480928,"about_ca_system_score_gemma":0.0002372491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006645129,"about_ca_topic_score_gemma":0.00101028,"domain_scores_codex":[0.999853,0.00001495392,0.0000144907,0.00003067036,0.00004853202,0.00003831328],"domain_scores_gemma":[0.9997875,0.00002649496,0.00005449676,0.00003627342,0.00002271834,0.00007252115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001115943,0.0007212135,0.0007958654,0.00007513726,0.00001056513,0.0001510914,0.00004510577,0.0001256676,0.9938534,0.0000889677,0.00007390045,0.002943187],"study_design_scores_gemma":[0.0001451196,0.007357713,0.009431854,0.00001094032,0.00006047166,0.0005282895,0.0001019574,0.0009075642,0.9787825,0.00006042295,0.002604438,0.000008864958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955105,0.0006377731,0.001970446,0.00006910958,0.00004950933,0.0001159149,0.00054898,0.00005858591,0.001039246],"genre_scores_gemma":[0.9923974,0.0009597742,0.002004746,0.00005710729,0.00001781719,0.0001313251,0.0008290049,0.00001937386,0.003583481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001486495,"threshold_uncertainty_score":0.004972756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0648656013213465,"score_gpt":0.3389867969998079,"score_spread":0.2741211956784614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}