{"id":"W4405495347","doi":"10.1093/ibd/izae227","title":"Improvement of Transmural Inflammation With Adalimumab Versus Immunomodulator Maintenance Therapy in Pediatric Crohn’s Disease: Single-Center Prospective Evaluation Using the Pediatric Inflammatory Crohn’s Magnetic Resonance Enterography Index","year":2024,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital; Hospital for Sick Children","funders":"AbbVie Canada; AbbVie","keywords":"Medicine; Adalimumab; Internal medicine; Crohn's disease; Prospective cohort study; Gastroenterology; Inflammatory bowel disease; Single Center; Magnetic resonance imaging; Thiopurine methyltransferase; Disease; Radiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003286088,0.000493926,0.0008565431,0.0005646005,0.0003594278,0.0005505153,0.0003360898,0.0004370723,0.0004018718],"category_scores_gemma":[0.00376425,0.0003056746,0.0007075891,0.0005953864,0.0003738382,0.0006654788,0.0003821339,0.0006159331,0.0001110091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004380682,"about_ca_system_score_gemma":0.0005206664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008944234,"about_ca_topic_score_gemma":0.001192462,"domain_scores_codex":[0.998675,0.0006758993,0.0001258657,0.0001988147,0.000221608,0.0001028299],"domain_scores_gemma":[0.9964742,0.0006609632,0.001776181,0.000162763,0.000321521,0.0006043831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.004910326,0.0005437,0.9892855,0.00003861887,0.0002002341,0.00007125473,0.00008777984,0.0001093267,0.0003946606,0.000007953571,0.00007098872,0.004279676],"study_design_scores_gemma":[0.0004044873,0.01357797,0.9843359,0.00001358052,0.0001574675,0.000448857,0.0001082701,0.0004631793,0.0003303674,0.000007782694,0.0001438436,0.000008317749],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995839,0.0002055603,0.00004499688,0.00001253395,0.00000296037,0.00001864478,0.00006902513,0.000002979925,0.00005932767],"genre_scores_gemma":[0.9992787,0.0001488705,0.0002423854,0.00001888614,0.00001225412,0.00004140707,0.0002220297,0.000001459789,0.00003396218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003286088,"threshold_uncertainty_score":0.01737875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009888952960697757,"score_gpt":0.2377675823805508,"score_spread":0.2278786294198531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}