{"id":"W4405510893","doi":"10.1097/dss.0000000000004470","title":"Efficacy and Safety of RelabotulinumtoxinA Liquid Botulinum Toxin in the Treatment of Lateral Canthal Lines: Results From the Phase 3 READY-2 Study","year":2024,"lang":"en","type":"article","venue":"Dermatologic Surgery","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Allergan; LEO Pharma; Galderma","keywords":"Medicine; Placebo; Adverse effect; Botulinum toxin; Patient satisfaction; Randomized controlled trial; Surgery; Internal medicine; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004423932,0.001331863,0.001742341,0.0003609668,0.0003282079,0.0007728913,0.0007338459,0.001126715,0.003372821],"category_scores_gemma":[0.002253558,0.0003626032,0.002194146,0.0002776249,0.0006994762,0.0007755728,0.0003189417,0.002046552,0.0005469056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007806259,"about_ca_system_score_gemma":0.000948029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008718108,"about_ca_topic_score_gemma":0.001726933,"domain_scores_codex":[0.9982585,0.001004053,0.0001355657,0.0001547679,0.0002838579,0.0001632603],"domain_scores_gemma":[0.9977514,0.0006436706,0.0008340384,0.0001806343,0.0002262077,0.0003640716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7717696,0.04331604,0.007565661,0.001966193,0.003322521,0.000203385,0.0003134897,0.0008013329,0.04420996,0.0001272036,0.002596678,0.1238078],"study_design_scores_gemma":[0.4768263,0.4826986,0.03200417,0.0001094654,0.001378464,0.000334855,0.00007472444,0.0005211747,0.004193927,0.00009258547,0.00172172,0.00004399171],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991513,0.004212965,0.0004446725,0.0002540699,0.00006708654,0.001387028,0.0009977834,0.00006503164,0.001058286],"genre_scores_gemma":[0.9916152,0.002493542,0.001100829,0.0007435432,0.0001831422,0.001178664,0.001694365,0.00004039635,0.000950415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004423932,"threshold_uncertainty_score":0.02339625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04611466727246013,"score_gpt":0.3143570672597195,"score_spread":0.2682423999872594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}