{"id":"W4405513972","doi":"10.1021/acsomega.4c09973","title":"Mechanistic Studies on the Gold-Catalyzed Intramolecular Hydroalkylation of Ynamides to Indenes","year":2024,"lang":"en","type":"article","venue":"ACS Omega","topic":"Catalytic Alkyne Reactions","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fonds Wetenschappelijk Onderzoek; Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture; Fonds De La Recherche Scientifique - FNRS; University of Ottawa","keywords":"Reactivity (psychology); Intramolecular force; Deprotonation; Chemistry; Hydride; Catalysis; Reaction mechanism; Computational chemistry; Combinatorial chemistry; Mechanism (biology); Stereochemistry; Hydrogen; Organic chemistry; Ion; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000247002,0.0005366415,0.0002712247,0.0001231018,0.0002311809,0.0002596663,0.0004714825,0.0002254194,0.002698254],"category_scores_gemma":[0.0003261045,0.0001174548,0.000325264,0.00009233797,0.0002758629,0.0005940789,0.000343956,0.0004776942,0.0003065942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00053226,"about_ca_system_score_gemma":0.0004139657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001796703,"about_ca_topic_score_gemma":0.003172766,"domain_scores_codex":[0.9999266,0.000007756804,0.000003428046,0.0000123955,0.00001844946,0.0000313015],"domain_scores_gemma":[0.9999459,0.00002408798,0.0000115121,0.000005069302,0.000008916507,0.000004475017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007565457,0.0004544565,0.003171456,0.002981182,0.000165198,0.002089337,0.0006000908,0.09875873,0.8068652,0.043879,0.001862689,0.03841614],"study_design_scores_gemma":[0.0001108768,0.001499979,0.003238812,0.0001193243,0.0001369778,0.000408711,0.0003463213,0.09513196,0.8814093,0.004462483,0.0130625,0.00007270963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794087,0.001840615,0.006173919,0.0001744282,0.00003467164,0.00006689261,0.0002724352,0.00009889369,0.01192943],"genre_scores_gemma":[0.9950984,0.00154924,0.002224454,0.00002495013,0.000004625053,0.00002814614,0.000154906,0.00001160213,0.0009036776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002698254,"threshold_uncertainty_score":0.009026527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02745492310179559,"score_gpt":0.2910119650890786,"score_spread":0.263557041987283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}