{"id":"W4405527665","doi":"10.1016/j.bbadva.2024.100132","title":"Best evidence linking the extracellular factor TGF-β to cancer-associated alternative splicing programs","year":2024,"lang":"en","type":"review","venue":"BBA Advances","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; U.S. Department of Defense","keywords":"Alternative splicing; Extracellular; Transforming growth factor; RNA splicing; Splicing factor; Cancer; Biology; Cancer research; Computational biology; Genetics; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004901252,0.0007106345,0.0007773889,0.0016301,0.0002317927,0.0008885856,0.0006637542,0.0009163482,0.004455489],"category_scores_gemma":[0.0005636939,0.0002485889,0.0002863008,0.001979591,0.0005304972,0.001115508,0.0006636717,0.001589052,0.003599994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005351867,"about_ca_system_score_gemma":0.00082493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004766512,"about_ca_topic_score_gemma":0.0006599664,"domain_scores_codex":[0.9998828,0.00001685501,0.00001652241,0.00003025309,0.00003952167,0.00001391412],"domain_scores_gemma":[0.9996595,0.0001581909,0.00004578267,0.00001432986,0.00008410544,0.00003802411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008526888,0.00004996896,0.0001674542,0.01298199,0.000061194,0.0003230762,0.00004902688,0.0002951031,0.004959826,0.008110017,0.02362122,0.9492958],"study_design_scores_gemma":[0.000008698775,0.00005570951,0.0005325925,0.001631982,0.00006164917,0.001053977,0.00003254882,0.00005301365,0.001402479,0.002859542,0.9922937,0.00001417225],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000117525,0.9975381,0.0002042404,0.0003661864,0.0002086245,0.000002549117,0.00001805855,0.000008784987,0.001536071],"genre_scores_gemma":[0.0005896292,0.9982848,0.0001910898,0.0001572926,0.0001736944,0.000003667729,0.00002738839,0.000001783551,0.0005706589],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004455489,"threshold_uncertainty_score":0.01490504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.10487266194442,"score_gpt":0.426519835214158,"score_spread":0.321647173269738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}