{"id":"W4405535653","doi":"10.1016/s2214-109x(24)00409-1","title":"Safety and immunogenicity of an acellular pertussis vaccine containing genetically detoxified pertussis toxin administered to pregnant women living with and without HIV and their newborns (WoMANPOWER): a randomised controlled trial in Uganda","year":2024,"lang":"en","type":"article","venue":"The Lancet Global Health","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; BC Children's Hospital","funders":"Medical Research Council; Foreign, Commonwealth and Development Office; Department for International Development; Department of Health and Social Care; BC Children’s Hospital Foundation; European and Developing Countries Clinical Trials Partnership; Wellcome Trust; BC Children's Hospital; Department for International Development, UK Government; Children's Hospital Foundation; Johns Hopkins University","keywords":"Immunogenicity; Medicine; Randomized controlled trial; Whooping cough; Pertussis toxin; Human immunodeficiency virus (HIV); Pertussis vaccine; Virology; Immunology; Pediatrics; Internal medicine; Vaccination; Immunization; Antibody; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004074809,0.001417843,0.002993227,0.0006220524,0.0005766791,0.0009703449,0.0008740858,0.002227757,0.003861555],"category_scores_gemma":[0.006287042,0.001013571,0.001831161,0.0005534833,0.00163916,0.001131951,0.0007829589,0.001611231,0.0003870909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008679198,"about_ca_system_score_gemma":0.001720378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001283052,"about_ca_topic_score_gemma":0.001660762,"domain_scores_codex":[0.9973118,0.001912306,0.00019312,0.0002476717,0.0001100883,0.0002250425],"domain_scores_gemma":[0.9978331,0.0008063257,0.0005973902,0.0001772567,0.0001283114,0.0004576152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9718017,0.006185682,0.0009630906,0.001973931,0.0008672818,0.00008352977,0.0002742576,0.0002557379,0.001844959,0.00009343736,0.0002327077,0.01542358],"study_design_scores_gemma":[0.8714673,0.1249765,0.001980728,0.0001233611,0.0004948308,0.0000382285,0.00005615132,0.0001386412,0.0002569149,0.0001067376,0.0003460353,0.00001454347],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896062,0.004013728,0.0003885561,0.0002637077,0.0002186587,0.00470276,0.0002411553,0.00003528293,0.000529805],"genre_scores_gemma":[0.9817837,0.002995256,0.001473113,0.0003771293,0.0001772823,0.01197773,0.0001940113,0.000009082537,0.001012761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004074809,"threshold_uncertainty_score":0.02154994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0142459660373284,"score_gpt":0.2834836291336436,"score_spread":0.2692376630963151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}