{"id":"W4405555514","doi":"10.21203/rs.3.rs-5449535/v1","title":"Central Nervous System Disease and Outcome in Pediatric Acute Myeloid Leukemia: Results from NOPHO-DBH AML2012 Trial","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Myeloid leukemia; Outcome (game theory); Disease; Medicine; Central nervous system; Oncology; Pediatrics; Immunology; Internal medicine; Economics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001171075,0.0004789707,0.001107565,0.0000999712,0.0001647561,0.0009219241,0.0004720807,0.0004207757,0.002626271],"category_scores_gemma":[0.002670114,0.0001446156,0.0009797142,0.0002659771,0.0003262507,0.0005599508,0.0005210995,0.001512176,0.0003567424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007516121,"about_ca_system_score_gemma":0.0007832432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001201203,"about_ca_topic_score_gemma":0.003056727,"domain_scores_codex":[0.9993305,0.0004041811,0.00002221161,0.00008964913,0.00006543826,0.00008811476],"domain_scores_gemma":[0.9988151,0.0003520475,0.0003364182,0.0001035581,0.00006202906,0.0003309206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6422372,0.002362974,0.0804086,0.003069585,0.01219544,0.0003128192,0.0001621118,0.005160267,0.005174062,0.00317242,0.0647072,0.1810374],"study_design_scores_gemma":[0.4145533,0.04089106,0.4567361,0.001311882,0.02104616,0.000758668,0.0003779531,0.004076071,0.003445609,0.01008428,0.04655787,0.0001610574],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.960628,0.01849216,0.0005065507,0.004770197,0.0005422785,0.0001467176,0.007625471,0.00006971707,0.007218973],"genre_scores_gemma":[0.981196,0.004512092,0.0005606359,0.001526907,0.0005451319,0.0001954209,0.008211004,0.00004617987,0.003206542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002626271,"threshold_uncertainty_score":0.008785725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05511240332611898,"score_gpt":0.3777305015892568,"score_spread":0.3226180982631378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}