{"id":"W4405564300","doi":"10.1016/j.bpsgos.2024.100435","title":"Electroencephalography Biomarkers of α5-GABA Positive Allosteric Modulators in Rodents","year":2024,"lang":"en","type":"article","venue":"Biological Psychiatry Global Open Science","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Brain Institute; Centre for Addiction and Mental Health","funders":"Krembil Foundation","keywords":"Allosteric regulation; Electroencephalography; Neuroscience; Chemistry; Biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007666977,0.0002802489,0.0001823031,0.0002010751,0.00005100546,0.0001193461,0.00008030542,0.0001676972,0.0005774386],"category_scores_gemma":[0.0001866053,0.00006171401,0.000101877,0.0001442478,0.0001284338,0.0001003667,0.00008950198,0.0002936893,0.00009388931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007894937,"about_ca_system_score_gemma":0.00006632994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000286652,"about_ca_topic_score_gemma":0.0005075824,"domain_scores_codex":[0.9999542,0.000008552208,0.000003651427,0.00001103507,0.00001373345,0.000008795287],"domain_scores_gemma":[0.9999148,0.000009130405,0.00004314703,0.000005822455,0.00001167456,0.00001548552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002276865,0.0001878219,0.01547023,0.0001169185,0.00007382283,0.0002583155,0.0000409968,0.0002057961,0.9508973,0.00007474276,0.0003044096,0.03009278],"study_design_scores_gemma":[0.0001594154,0.01141007,0.5986648,0.00004207174,0.0002374995,0.001580234,0.0001886789,0.001718989,0.3830903,0.0002670869,0.002612929,0.00002793544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917236,0.002527279,0.003769185,0.00008277132,0.00003125928,0.00005958298,0.0004429682,0.0001084659,0.001254892],"genre_scores_gemma":[0.9948933,0.00164634,0.002048226,0.0001442944,0.00001656875,0.00007334832,0.0003756396,0.000007543724,0.0007947381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005774386,"threshold_uncertainty_score":0.001931787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05549113034612591,"score_gpt":0.3983952766047475,"score_spread":0.3429041462586216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}