{"id":"W4405577943","doi":"10.1096/fj.202401747r","title":"Transcriptomic and lipidomic profiling reveals distinct bioactive lipid signatures in slow and fast muscles and highlights the role of resolvin‐ <scp>D2</scp> in fiber type determination during myogenesis","year":2024,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Université Laval; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada","keywords":"Myogenesis; Myosin; Skeletal muscle; Soleus muscle; Docosahexaenoic acid; Myocyte; Biochemistry; Lipidomics; Chemistry; Eicosapentaenoic acid; Biology; Arachidonic acid; Lipid signaling; Internal medicine; Cell biology; Endocrinology; Fatty acid; Polyunsaturated fatty acid; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003984834,0.0001072327,0.0001288317,0.00009993471,0.00009605908,0.00005915924,0.00007726296,0.00008449068,0.000001988053],"category_scores_gemma":[0.00005845295,0.00006656577,0.00003130522,0.00009733967,0.00008627345,0.00001687278,0.00003582298,0.0001654676,1.875421e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009743673,"about_ca_system_score_gemma":0.00002167783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000197056,"about_ca_topic_score_gemma":0.0000626233,"domain_scores_codex":[0.9992533,0.0001651102,0.0001962714,0.0001694073,0.00007942595,0.0001364242],"domain_scores_gemma":[0.9997094,0.00007717453,0.00006409073,0.00008499354,0.00002953404,0.00003481662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008371957,0.00001430966,0.002211115,0.00006584002,0.00001701306,0.000003809372,0.0005539727,0.000006893729,0.9882512,0.00002572647,0.00001058843,0.008755785],"study_design_scores_gemma":[0.0006064726,0.00007498562,0.1274337,0.0001708138,0.00004308805,0.00007300919,0.000540347,0.0004292959,0.8696936,0.000363534,0.0005121031,0.00005900171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9755123,0.02406499,0.00001233863,0.00008910737,0.00009147641,0.000156741,0.00001912049,0.00000306388,0.00005080856],"genre_scores_gemma":[0.9956046,0.003935121,0.00009997023,0.00001186987,0.0002447968,0.000006338267,0.000005809135,0.00001205391,0.00007940668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1252226,"threshold_uncertainty_score":0.2714474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005706942609421272,"score_gpt":0.2166604298888248,"score_spread":0.2109534872794035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}