{"id":"W4405611656","doi":"10.1055/s-0043-1774256","title":"Effects of STW3-VI (St. John's wort) on molecular mechanisms of depression in vitro","year":2023,"lang":"en","type":"article","venue":"Planta Medica","topic":"Natural Compound Pharmacology Studies","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"In vitro; Depression (economics); Traditional medicine; Chemistry; Medicine; Pharmacology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002278716,0.00009767929,0.000237163,0.00003493499,0.00004049457,0.000002190917,0.00021155,0.00008591473,0.00004528095],"category_scores_gemma":[0.0001286801,0.00003626691,0.00004973719,0.0003725703,0.00005587004,0.00002114088,0.0001132991,0.0001578264,0.00001063293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001036892,"about_ca_system_score_gemma":0.000004845258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007384946,"about_ca_topic_score_gemma":0.00002434892,"domain_scores_codex":[0.9990398,0.0001105452,0.0001769455,0.0001837382,0.0002897463,0.0001992187],"domain_scores_gemma":[0.9988757,0.0009339682,0.00008643453,0.00003395537,0.00001774222,0.00005223642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001490061,0.00007078139,0.0005129722,0.00003584414,0.00002147392,0.00009352748,0.0000336535,0.000001892771,0.9902663,0.00006180679,0.00143078,0.00732201],"study_design_scores_gemma":[0.000313518,0.00017523,0.05650096,0.0001027594,0.0000182412,0.000002394986,0.00004373779,0.00004606158,0.9410609,0.0009722875,0.0006835747,0.00008032777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982442,0.0003162876,0.000001560863,0.0005978592,0.000240495,0.0001907653,0.00003872656,0.00003704151,0.0003330141],"genre_scores_gemma":[0.9994504,0.0001899144,0.00002856296,0.0001964554,0.00003396963,0.00001688835,0.00005472916,7.442941e-7,0.00002832349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05598799,"threshold_uncertainty_score":0.1478921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01031821687334871,"score_gpt":0.244523621330255,"score_spread":0.2342054044569063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}