{"id":"W4405638461","doi":"10.1016/j.medj.2024.11.013","title":"Molecular insights into trauma: A framework of epigenetic pathways to resilience through intervention","year":2024,"lang":"en","type":"review","venue":"Med","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital","funders":"National Institute on Minority Health and Health Disparities; National Institute of General Medical Sciences","keywords":"Biopsychosocial model; Psychological resilience; Psychological intervention; Adaptation (eye); Intervention (counseling); Psychology; Epigenetics; Dynamism; Maladaptation; Thriving; Medicine; Psychotherapist; Neuroscience; Biology; Psychiatry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009488956,0.0009324703,0.001161451,0.00155013,0.0002731541,0.00112992,0.001206381,0.001690497,0.003085779],"category_scores_gemma":[0.001185093,0.0001960648,0.0004006729,0.001351422,0.001031341,0.001152153,0.0009385505,0.002554795,0.001023005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001094352,"about_ca_system_score_gemma":0.001387657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001230662,"about_ca_topic_score_gemma":0.002678212,"domain_scores_codex":[0.9998135,0.00005148365,0.00001877542,0.0000348205,0.00005969679,0.00002166984],"domain_scores_gemma":[0.9995775,0.0002680096,0.00003532106,0.0000140638,0.00007544053,0.00002971397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009913815,0.00006430545,0.0001642207,0.009566437,0.0001241766,0.0002153163,0.00006856171,0.0006459073,0.00168693,0.02511866,0.03991672,0.9223296],"study_design_scores_gemma":[0.00003308572,0.00009968921,0.0007312203,0.004681303,0.0001236781,0.0008996938,0.00010413,0.0002306503,0.0007890987,0.01447196,0.9778094,0.00002613861],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004555939,0.9977963,0.0002893683,0.0008778935,0.0003292999,0.000002799197,0.000009888748,0.000005775966,0.0006431504],"genre_scores_gemma":[0.0006875035,0.9976163,0.0003015768,0.0003930217,0.0004547645,0.000006837373,0.00001307449,0.000001304993,0.0005257246],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003085779,"threshold_uncertainty_score":0.01032299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03027183763290928,"score_gpt":0.3493706087158966,"score_spread":0.3190987710829873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}