{"id":"W4405642879","doi":"10.3390/molecules29246002","title":"Novel Copper(II) Coordination Compounds Containing Pyridine Derivatives of N4-Methoxyphenyl-Thiosemicarbazones with Selective Anticancer Activity","year":2024,"lang":"en","type":"article","venue":"Molecules","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Chemistry; Semicarbazone; HeLa; Molar conductivity; Stereochemistry; Selectivity; Copper; Carbon-13 NMR; Pyridine; Proton NMR; Denticity; Ligand (biochemistry); Medicinal chemistry; Metal; Organic chemistry; In vitro; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002478492,0.000205814,0.0004777302,0.0001154986,0.0001113876,0.00003757907,0.00007770309,0.00006215359,0.00003285769],"category_scores_gemma":[0.0001424975,0.0001422889,0.00008900153,0.0003637646,0.000247778,0.0001489141,0.00005832314,0.0001912375,0.000002552168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006380001,"about_ca_system_score_gemma":0.0001387218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001261714,"about_ca_topic_score_gemma":0.00001775219,"domain_scores_codex":[0.9988736,0.00007999687,0.0002160204,0.0003209807,0.0003055636,0.0002038508],"domain_scores_gemma":[0.9991643,0.0002553818,0.00008824087,0.0001801135,0.0002540714,0.00005789513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007367458,0.0001388695,0.001354509,0.0002710983,0.0003376434,0.000007898911,0.001071414,0.00001756724,0.987542,0.004419274,0.0001854484,0.00391747],"study_design_scores_gemma":[0.0006604947,0.001358939,0.01664166,0.0008820517,0.0002135053,0.00006585973,0.0003639919,0.005015823,0.972048,0.0001913847,0.002336486,0.0002218471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741188,0.001682925,0.01589939,0.001323497,0.00007472387,0.0003046635,0.00002140782,0.0001010317,0.006473596],"genre_scores_gemma":[0.9911286,0.00003544515,0.008310631,0.0001081455,0.00006477516,0.00003161945,0.00001162984,0.00003795746,0.0002712202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01700981,"threshold_uncertainty_score":0.5802372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03828597622644401,"score_gpt":0.2919093505358354,"score_spread":0.2536233743093914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}