{"id":"W4405655654","doi":"10.1002/cbf.70036","title":"Epigenetic Regulation by Histone Methylation and Demethylation in Freeze‐Tolerant Frog Kidney","year":2024,"lang":"en","type":"article","venue":"Cell Biochemistry and Function","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Histone methyltransferase; Histone; Epigenetics; Biology; Histone methylation; Demethylation; Methylation; Cell biology; Methyltransferase; Cancer epigenetics; Histone H4; Histone H3; Histone H2A; Gene expression; Biochemistry; DNA methylation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003302504,0.00018862,0.00012713,0.00007587384,0.00008699945,0.00006844998,0.00004231382,0.0003064958,0.00002911458],"category_scores_gemma":[0.000058239,0.000200657,0.0000400645,0.0001561767,0.00006840229,0.0000157553,0.0000387913,0.0001247576,0.00000387645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003529617,"about_ca_system_score_gemma":0.00005196602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003484484,"about_ca_topic_score_gemma":0.000006654123,"domain_scores_codex":[0.9988161,0.00005850803,0.0002816486,0.0005444509,0.0001259402,0.0001733398],"domain_scores_gemma":[0.9995563,0.00002551977,0.00006702013,0.0001861951,0.00004585143,0.0001191187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005927259,0.00002766994,0.001759078,0.0001457065,0.00001391188,6.730426e-7,0.00005415698,0.00008159264,0.9785429,0.00001937602,0.0006964158,0.01859925],"study_design_scores_gemma":[0.0004162642,0.0001353833,0.004698179,0.00004229489,0.00004317006,0.000002330958,0.00003271746,0.003981757,0.9631021,0.0008179648,0.02649176,0.0002360615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9310449,0.03821551,0.02909653,0.0001766611,0.0002555554,0.0001725308,0.00002531453,0.00002817802,0.0009848659],"genre_scores_gemma":[0.9951921,0.00178618,0.0003864309,0.00005692244,0.0002068272,0.00002320185,0.001021814,0.00002441232,0.001302085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06414727,"threshold_uncertainty_score":0.8182557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005442075960342805,"score_gpt":0.2269726712021422,"score_spread":0.2215305952417994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}