{"id":"W4405699137","doi":"10.1039/d4ay01921k","title":"Advances in human papillomavirus detection for cervical cancer screening and diagnosis: challenges of conventional methods and opportunities for emergent tools","year":2024,"lang":"en","type":"review","venue":"Analytical Methods","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Engineering and Physical Sciences Research Council; National Research Foundation; Cancer Research UK","keywords":"Human papillomavirus; Cervical cancer; Cervical cancer screening; Cancer detection; Cancer; Medicine; Computational biology; Medical physics; Risk analysis (engineering); Computer science; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003068381,0.0003362835,0.002185522,0.0004282071,0.00007367168,0.00003472174,0.00009679938,0.0003343771,0.0002518013],"category_scores_gemma":[0.000892086,0.000251633,0.0005669783,0.0002202802,0.0002448194,0.0001006261,0.0001340437,0.0004386553,1.6616e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009565424,"about_ca_system_score_gemma":0.000156498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004057035,"about_ca_topic_score_gemma":0.0001180866,"domain_scores_codex":[0.9972611,0.0006152756,0.0008904323,0.0006238801,0.0002526875,0.0003565933],"domain_scores_gemma":[0.9958096,0.003381113,0.0001474981,0.0001856583,0.0002156052,0.000260593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001120705,0.00005409838,0.000007258008,0.06533532,0.0003531146,0.00000427345,0.00002231256,1.938264e-7,0.000002596677,0.0104441,0.00002599745,0.9236386],"study_design_scores_gemma":[0.0008570279,0.0007157305,0.0001822968,0.006337034,0.004303642,0.00001318033,0.0001967199,0.001383444,0.00006467818,0.005523837,0.9801311,0.0002912726],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000003021271,0.9510126,0.04612864,0.0006845782,0.0001358963,0.001376412,0.0001447484,0.00001853361,0.0004955672],"genre_scores_gemma":[0.00002768988,0.9384819,0.05803344,0.00004328358,0.0003230711,0.002862263,0.00003626699,0.00005192795,0.0001401649],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9801052,"threshold_uncertainty_score":0.9999936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5487664732815747,"score_gpt":0.6152151672908389,"score_spread":0.06644869400926423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}