{"id":"W4405704089","doi":"10.3390/nu16244407","title":"Obesity and Metabolic Disease Impair the Anabolic Response to Protein Supplementation and Resistance Exercise: A Retrospective Analysis of a Randomized Clinical Trial with Implications for Aging, Sarcopenic Obesity, and Weight Management","year":2024,"lang":"en","type":"article","venue":"Nutrients","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Medicine; Sarcopenia; Internal medicine; Sarcopenic obesity; Obesity; Overweight; Body mass index; Metabolic syndrome; Anabolism; Lean body mass; Endocrinology; Body weight","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009988666,0.0007585909,0.001747297,0.0004650745,0.0004573929,0.0009400396,0.0005185296,0.0007236834,0.001422649],"category_scores_gemma":[0.01045886,0.0005728765,0.002875356,0.0006984813,0.0008786223,0.000521069,0.0004972874,0.0008857121,0.0002068384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004877939,"about_ca_system_score_gemma":0.001018811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005842355,"about_ca_topic_score_gemma":0.0009287375,"domain_scores_codex":[0.9911727,0.005615018,0.001105469,0.001103274,0.0007182804,0.0002852309],"domain_scores_gemma":[0.9890332,0.003926059,0.003662589,0.002042862,0.0005524343,0.0007827754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6138097,0.002910159,0.3463919,0.0006335734,0.02130469,0.0001953226,0.000154869,0.0005903448,0.00304235,0.000207815,0.0005295858,0.01022958],"study_design_scores_gemma":[0.1487719,0.09665188,0.7123098,0.0001933188,0.03151966,0.0006883676,0.0002446663,0.004101315,0.002307489,0.0004446029,0.002663601,0.0001034631],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959918,0.001949061,0.000813147,0.00006151254,0.00005589266,0.0004911715,0.0004028321,0.00001346976,0.0002212287],"genre_scores_gemma":[0.9978442,0.0002908399,0.0006666408,0.0001005932,0.00005975823,0.0004091931,0.0004800168,0.000004978084,0.0001438454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009988666,"threshold_uncertainty_score":0.05282575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0108691674289906,"score_gpt":0.3181967105512887,"score_spread":0.3073275431222981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}